Description
Pharmacological action of
Pharmacotherapeutic group: antimicrobial combination agent
ATX code [D06BX]
Pharmacological properties
Oflomelide ® combination drug has an antimicrobial, anti-inflammatory, local anesthetic, regenerative effect. The active substances are ofloxacin, methyluracil and lidocaine.
Ofloxacin is a broad-spectrum antimicrobial agent from the group of fluoroquinolones. It has a bactericidal effect due to the blockade of DNA gyrase in bacterial cells. Active against gram-negative and gram-positive microorganisms.
Methyluracil tissue repair stimulator. It has anabolic activity.
Accelerates the processes of cellular regeneration in wounds, accelerating the growth and granulation tissue maturation and epithelization.
Lidocaine has a local anesthetic effect due to blockade of Na + channels, which prevents the generation of impulses at the ends of sensitive neurons and the conduction of impulses along nerve fibers. When applied externally, dilates blood vessels, does not have a local irritant effect.
The basis of the ointment is a mixture of polyethylene oxides with a molecular weight of 400 and 1500, which provides a dehydrating effect on the tissue 20 times greater than the strength of the 10% sodium chloride solution.
Indications
An antimicrobial agent is prescribed for purulent, infected wound lesions of various etiologies and localization in the purulent necrotic (first) phase of the wound healing process, including concomitant pain syndrome:
trophic ulcers
sores of
grade 2 sores after surgical opening of phlegmon and
abscesses after surgical treatment of hydradenitis, carbuncles, abscessed boils, suppurative lipomas and atheroma
post-traumatic and postoperative soup and wounds.
Contraindications
Lactation
pregnancy
individual hypersensitivity
age limit – up to 18 years.
Composition
Composition 100 g: active substances: ofloxacin – 1 g, dioxomethyl tetrahydropyrimidine (methyluracil) – 4 g, lidocaine hydrochloride monohydrate (in terms of lidocaine hydrochloride) – 3 g
excipients: methyl parahydroxybenzoate (nipagin or methyl paraben), propyl parahydroxybenzoate (nipazole or propyl paraben), propylene glycol, macrogol-1500-1500-polyethylene glycol, polyethylene glycol, 1500 polyethylene glycol (low molecular weight polyethylene glycol-400, polyethylene oxide-400).
Drug Interactions
There have been no cases of drug interactions that would reduce the effectiveness and safety of the drugs used.
Storage conditions
In the dark place at a temperature of 15 to 25 ° C.
Keep out of the reach of children.
Expiration
2 years.
Terms of delivery from pharmacies
Prescription
Dosage form
ointment
