Description
Pharmacological action of
Topical glucocorticosteroid
Indications
Inflammatory skin diseases that are sensitive to topical glucocorticosteroid therapy: atopic dermatitis, neurodermatitis, childhood eczema true eczema microbial eczema simple contact dermatitis allergic (contact) dermatitis dyshidrotic eczema.
Special instructions
For bacterial dermatoses / dermatomycoses, in addition to Comfoderm K, specific antibacterial or antimycotic treatment is required.
Cream is not intended for use in ophthalmology. Avoid contact with mucous membranes and eyes.
After external use of Komfoderm K, glaucoma may develop (for example, during high-dose therapy, due to application to the skin around the eyes or very long-term use of occlusive dressings).
Composition
Composition 100 mg cream:
active substance:
aceponate methylprednisolone – 0.1 mg (in terms of 100% substance)
auxiliary components:
macrogol stearate 40 – 1.5 mg
glyceryl monostearate 8 mg
potassium dihydrogen phosphate – 0.49 mg
ceramide – 0.5 mg
preservative Euxyl PE 9010 (ethylhexyl glycerol – 10%, phenoxyethanol – 90%) – 0.9 mg (in terms of phenoxyethanol) sodium
dodecahydrate 0,01 sodium mg
isopropyl myristate – 7 mg
edetate disodium – 0.1 mg
octyldodecanol – 7 mg
hexyl decyl stearate – 7 mg s rdlkp dimethicone 100 cst – 1 mg
cetostearyl alcohol (stearyl alcohol – 40%, cetyl alcohol – 60%) – 2 mg
propylene glycol – 7 mg
purified water – up to 100 mg.
Dosage and Administration
Externally. Adults and children from 4 months of age.
The drug is applied 1 time per day with a thin layer on the affected skin. Usually, the duration of continuous daily treatment with Comfoderm ® K should not exceed 12 weeks for adults and 4 weeks for children.
The Comfoderm ® K preparation is suitable for the treatment of subacute and acute inflammatory processes without pronounced wetting, with localization of the process both on smooth skin and on the scalp, including on skin prone to oily.
Side effects
The incidence of side effects is classified according to the recommendations of the World Health Organization (WHO):
very often ( 10%),
often ( 1%, <10%), infrequently ( 0.1% , <1%), rarely ( 0.01%, <0.1%), very rare (<0.01%), frequency is unknown (it is not possible to estimate the frequency of occurrence). Disorders from the skin and subcutaneous tissues: rarely perioral dermatitis, skin depigmentation, allergic reactions to the drug components, frequency of atrophy of the skin, telangiectasia, striae, acne-like skin changes (when using the drug for more than 4 weeks and / or on an area of ² ¹ ² ¹10% and over the surface of the body). General disorders and disorders at the injection site: rarely – folliculitis, hypertrichosis very rarely – itching, burning, erythema, formation of a vesicular rash, frequency is unknown – systemic effects due to absorption of glucocorticosteroid (when using the drug for more than 4 weeks and / or on an area of ² ¹ ² ¹10 % or more of the surface of the body). If any of the side effects listed in the instructions get worse, or any other side effects not indicated in the instructions are noted, you should immediately inform your doctor. Storage conditions At a temperature not exceeding 25 ° C. Keep out of the reach of children. Active ingredient Methylprednisolone aceponate, Urea Dosage form cream
