Description
Pharmacological action
The mechanism of action included in the drug, fipronil, is to block the GABA-dependent ectoparasite receptors, impaired transmission of nerve impulses, which leads to paralysis and death of ectoparasites. Diflubenzuron, inhibiting chitin synthesis in parasites, disrupts the molting process, oviposition and hatchability of larvae from eggs, which leads to the termination of replenishment of the population. Dicarboximide is a synergist and is used with insecticides to increase their activity. Dicarboximide stops microsomal detoxification of the insecticide, increasing its toxicity to the parasite.
After the cutaneous application of the drug, the active substances included in its composition, not being absorbed into the systemic circulation, are evenly distributed over the surface of the body, accumulate in the sebaceous glands, protecting the animal for a long time from ectoparasites.
Insecticide and acaricidal drops of Bars are classified as moderately hazardous substances by the degree of exposure to the body at recommended doses, they do not have a resorptive-toxic, local irritant and sensitizing effect if they come into contact with the eyes. The drug is well tolerated by dogs and cats of different breeds and ages, but is toxic to rabbits, as well as fish and other aquatic organisms.
Indications
Assign to dogs and cats from 8 weeks of age for the treatment and prevention of entomoses (lice, fleas, lice-eaters), sarcoptosis, notoedrosis, otodectosis, cheyletiellosis, ixodid ticks.
Contraindications
Individual hypersensitivity of the animal to the components of the drug. Patients with infectious diseases, weakened and recovering animals, pregnant and lactating females, as well as puppies and kittens younger than 8 weeks of age, dogs weighing less than 2 kg should not be treated. BARS ® drops against fleas and ticks should not be used auricularly when perforated eardrum.
Special instructions
Do not wash or bathe the animal for 3 days before and after treatment, or apply the drug to wet or damaged skin.
Composition
BARS ® drops against fleas and ticks for dogs contain fipronil 50 mg / ml, diflubenzuron 1 mg / ml and dicarboximide (MGK-264) 5 mg / ml as active ingredients.
Dosage and administration
Apply to animals once by drop application to dry intact skin at several points in the back between the shoulder blades or in the neck at the base of the skull (to places inaccessible for licking to animals) in the doses indicated in the table.
Type and weight of the animal
The volume of the drug in a pipette, ml
The dose of the drug, ml per animal
The number of pipettes needed for processing, pieces
Dogs
of the corresponding volume
with a volume of 1.4 ml
from 2 to 10 kg
1.4
1.4
1
10 to 20 kg
2.8
2.8
1
2
20 to 30 kg
4.2
4, 2
1
3
over 30 kg
5
5-10
1-2
4-7
When treating large dogs (over 30 kg), BARS ® drops against fleas and ticks are dosed at a rate of 0.1 ml / kg, using pipettes of different volumes.
The protective effect of the drug lasts for 1-2 months. Repeated treatment of animals is carried out according to indications, but not more than once a month.
In the treatment of otodectosis, the auricles and ear canal are first cleaned of earwax, exudate and scabs, then 4-6 drops of the drug are instilled into each ear. To evenly distribute the drug, the auricle is folded along and its base lightly massaged. The remainder of the drug in a pipette is applied to the animal on the skin between the shoulder blades. In the advanced case of otodectosis complicated by otitis media, prescribe antibacterial and anti-inflammatory drugs and repeat the auricular use of BARS ® drops against fleas and ticks after 7-10 days.
The drug must be administered in both ears, even in cases of only one ear being affected by otodectosis.
To prevent the drug from splashing (if the animal shakes its head), the animal’s head should be fixed for several minutes.
In order to prevent re-infestation with fleas, the animals are replaced with litter or they are treated and the floors of the premises with any insecticidal agent in accordance with the instructions for its use.
Side effects
Side effects and complications when using the drug in accordance with the instructions, as a rule, are not observed.
In case of increased individual sensitivity to the active components of the drug or overdose, it should be washed off with water and a detergent and prescribed antihistamines and symptomatic agents to the animal.
Storage conditions
Store the drug in the manufacturer s closed packaging, in a place protected from light and moisture, separately from food and feed, at a temperature of 0 ° C to 30 ° C.
Insecticide drops “Bars” should be kept out of the reach of children.
Shelf life
2 years.
Active ingredient
Fipronil, diflubenzuron, dicarboximide
