Description
Pharmacological action
Blocker of histamine H1 receptors (long-acting).
Is the primary active metabolite of loratadine.
Inhibits the release of histamine and leukotriene C4 from mast cells.
Prevents development and facilitates the course of allergic reactions. It has anti-allergic, antipruritic and anti-exudative action.
Reduces the permeability of capillaries, prevents the development of tissue edema, relieves spasm of smooth muscles. It practically does not have a sedative effect and, when taken at a dose of 7.5 mg, does not affect the rate of psychomotor reactions.
In comparative studies of desloratadine and loratadine, there were no qualitative or quantitative differences in the toxicity of the two drugs in comparable doses (taking into account the concentration of desloratadine).
Indications
Seasonal allergic rhinitis, chronic idiopathic urticaria.
Contraindications
Phenylketonuria, pregnancy, lactation, children under 1 year of age, hypersensitivity to desloratadine.
Special instructions
Desloratadine is prescribed with caution in severe renal failure.
Influence on the ability to drive vehicles and control mechanisms
Adverse effects on driving or on complex technical devices were not noted.
Composition
1 tablet contains:
active ingredient:
desloratadine – 5 mg
auxiliary components:
croscarmellose sodium lemon srrdlkp acids,
mannitol,
polacryline potassium,
magnesium stearate,
dye iron oxide red,
microcrystalline cellulose,
flavoring tutti-frutti (maltodextrin, modified starch E1450, propylene glycol.
Side effects
From the nervous system: headache, hallucinations, psychomotor hyperreactivity, convulsions.
From the digestive system: dry mouth, hepatitis.
Other: photosensitization, myalgia, shortness of breath, feeling tired.
active substance
desloratadine
Terms of delivery from
pharmacies Without a prescription
Dosage form
oral solution
Indications
Nasmork, Krapyvnytsa, Pollynoz, dermatitis, conjunctivitis, Dyatez, Allerhyya, Allerhycheskyy conjunctivitis, Allerhycheskyy rynyt
