Description
Release form
Nasal drops 0.05% as a clear, colorless or light yellow liquid.
Pharmacological action
Decongestant – alpha-adrenergic agonist.
Indications
Acute respiratory infections with rhinitis (runny nose), acute allergic rhinitis, hay fever, sinusitis, eustachitis, otitis media (to reduce swelling of the mucous membrane of the nasopharynx).
Preparing the patient for diagnostic procedures in the nasal passages.
Contraindications
– hypersensitivity to the drug,
– arterial hypertension,
– tachycardia,
– severe atherosclerosis,
– glaucoma,
– atrophic rhinitis,
– hyperthyroidism,
– surgical interventions on the meninges (history),
– condition after transsphenoid hypophysectomy,
– children under 2 years old – for a solution of 0.05% concentration,
children under 6 years old – for a solution with a concentration of 0.1%,
– pregnancy.
Do not use with monoamine oxidase inhibitors (MAOs) and tricyclic antidepressants, as well as with other drugs that increase blood pressure.
With caution
Diabetes mellitus, prostatic hyperplasia, coronary heart disease (angina pectoris) pheochromocytoma, lactation, with increased sensitivity to adrenergic drugs, accompanied by insomnia, dizziness, arrhythmia, tremor, high blood pressure.
Use during pregnancy and lactation
The use of the drug during pregnancy is contraindicated.
It is possible to use it for the treatment of nursing mothers as prescribed by the attending physician if the expected therapeutic effect in the mother exceeds the risk of developing possible side effects in the child.
Special instructions
Clean the nasal passages before use.
Do not exceed recommended doses and use the drug for a long (more than 7 days) time. The use of the drug for more than 7 days can cause a “rebound” effect (drug rhinitis).
With prolonged use of the drug, the risk of reactive hyperemia and atrophy of the nasal mucosa increases.
Since the drug contains benzalkonium chloride as a preservative, especially with prolonged use (more than 7 days), swelling of the nasal mucosa can develop. If you suspect a similar reaction (nasal congestion), it is necessary, if possible, to use a drug that does not contain preservatives. If such drugs are not available, you must use a different dosage form.
For “colds” in cases where crusts form in the nose, it is preferable to prescribe in the form of a gel.
Influence on the ability to drive vehicles and mechanisms
Xylometazoline may affect the ability to drive vehicles or equipment.
When treating with the drug, care must be taken when driving vehicles and engaging in other potentially dangerous activities that require increased concentration of attention and speed of psychomotor actions.
Composition of
1 ml of the preparation contains: Active ingredient:
Xylometazoline hydrochloride 0.5 mg
Excipients:
Benzalkonium chloride 0.15 mg
Disodium edetate dihydrate (trilon B) 0.5 mg sidlfid 3.5 mg srdlk hydrate
Potassium dihydrogen phosphate 3.63 mg
Sodium chloride 9.0 mg
Water for injection up to 1 ml
Dosage and Administration
Intranasally (in each nasal passage).
A solution of the drug at a concentration of 0.05%: children – from 2 to 6 years old – 1-2 drops in each nasal passage 1-2 times a day should not be used more than 3 times a day.
The drug is used no more than 7 days.
Side effects
With frequent and / or prolonged use – irritation and / or dryness of the nasopharyngeal mucosa, burning, tingling, sneezing, hypersecretion of the nasopharyngeal mucosa, hypersensitivity reactions, swelling of the nasal mucosa, feeling of palpitations, tachycardia, and blood pressure, headache, nausea, vomiting, insomnia, impaired vision, depression (with prolonged use of high doses).
If any of the side effects indicated in the instructions are aggravated or you notice any other side effects not listed in the instructions, inform your doctor.
Drug interaction
Simultaneous administration of xylometazoline with monoamine oxidase inhibitors (MAOs) and tricyclic antidepressants can lead to increased blood pressure, therefore, the simultaneous use of these drugs is not recommended.
Overdose
Strengthening of side effects (dose-dependent), decrease in body temperature, confusion.
In case of accidental ingestion, the drug may cause: severe dizziness, excessive sweating, headache, bradycardia, an increase in blood pressure, respiratory depression, coma and convulsions after an increase in blood pressure, a sharp decrease can be observed.
Treatment: symptomatic.
Active ingredient
Xylometazoline
Terms and conditions
without prescription
dosage form
nasal drops
Grotex Ltd. LLC, Russia
