Description
Pharmacological action
Amoxicillin, which is part of the drug, is a semisynthetic penicillin antibiotic. The mechanism of its action is to disrupt the synthesis of the bacterial cell wall by inhibiting the transpeptidase and carboxypeptidase enzymes, which leads to disruption of the osmotic balance and destruction of the bacterium. Amoxicillin has a wide spectrum of bactericidal action against gram-positive and gram-negative microorganisms such as Actynomyces spp., Bacillus antracis, Clostridium spp., Corynebacterium spp., Erysipelothrix rhusiopathiae, Listeria monocytogenes, Staphylococococpppppp. , Salmonella spp., Fusobacterium spp., Haemophilus spp., Moraxella spp., Pasteurella spp., Proteus mirabilis, Leptospira spp. Amoxicillin trihydrate is well absorbed from the injection site and is rapidly distributed in the body, reaching the highest concentration in the muscles, liver and kidneys. The maximum concentration in the blood is achieved 1-2 hours after the administration of Amoxicillin 15%, and remains at the therapeutic level for 48 hours. Amoxicillin is excreted mainly in the urine. Amoxicillin 15% in terms of exposure to the body belongs to moderately hazardous substances (hazard class 3 according to GOST 12.1.007).
Indications
– for cattle, sheep, pigs and goats for the treatment of bacterial infections of the respiratory tract, genitourinary system, skin and soft tissue diseases caused by microorganisms sensitive to amoxicillin.
Contraindications
– Individual hypersensitivity to beta-lactam antibiotics.
Special instructions
Slaughter of animals for meat is allowed no earlier than 14 days after the last use of the drug. The meat of animals forced to be killed before the expiration of this period can be used to feed fur animals or produce meat and bone meal. It is forbidden to use milk obtained from animals for food purposes during treatment with Amoxicillin 15% and within 48 hours after stopping the use of the drug. Milk obtained before the expiration of the indicated period can be used for feeding animals.
Composition
1 ml of amoxicillin (in the form of trihydrate) 150 mg Excipients: bottled hydroxytoluene – 1 mg, benzyl alcohol – 10 mg, aluminum monostearate – 15 mg, fractionated coconut oil – up to 1 ml.
necessary for
to achieve a sufficient depth of anesthesia Dosage and administration
The drug is used at a dose of 1 ml per 10 kg of animal weight (15 mg of active substance per 1 kg of animal weight) v / m. If necessary, re-administration of the drug after 48 hours is possible.
Side effects
Side effects and complications when using Amoxicillin 15% at the recommended doses are not observed.
dosage form
injection
