Description
Release form
Solution for external use.
Packing
Bottle 15 ml.
Pharmacological action
Clotrimazole – trichomonacid, antiprotozoal, antifungal, antibacterial.
Destroys the cytoplasmic membrane of microorganisms with the formation of vacuoles inside the cell, inhibits the synthesis of nucleic acids and proteins.
Pharmacodynamics
It has a wide range of fungicidal effects: effective against yeast (Candida albicans) and mold (phycomycetes) fungi, dermatophytes (including Trichophyton, Epidermophyton, Microsporum), Malassezia furfur includes an antibacterial spectrum. h Corynebacterium minutissima.
Pharmacokinetics
Poorly absorbed from the skin and mucous membranes. Accumulates in the stratum corneum of the epidermis.
Indications
– Fungal lesions of the skin and mucous membranes.
– Mycosis of the feet / hands, smooth skin of the trunk, limbs, folds, beard, mustache, scalp caused by dermatophytes.
– Pityriasis versicolor, spectra, candidiasis of the skin, genital mucosa, paronychia.
Contraindications
Hypersensitivity to clotrimazole, I trimester of pregnancy.
Use during pregnancy and lactation
In clinical and experimental studies, it was not found that the use of clotrimazole during pregnancy and lactation has a negative effect on the health of a woman or fetus (child). However, the question of the advisability of prescribing clotrimazole should be decided individually after consulting a doctor. In case of prescribing the drug to a pregnant woman, she should be warned that with the introduction of vaginal tablets, the applicator should not be used.
Composition of
1 ml of solution contains:
Active substance:
clotrimazole 10 mg
Excipients:
isopropyl myristinate,
ethanol anhydrous.
Dosage and Administration
Topically. For adults and children, a few drops of the solution are applied in a thin layer to the cleaned and dry affected and surrounding areas of the skin 2 times a day (morning and evening) and rubbed thoroughly. After eliminating the acute symptoms of the disease, treatment should be continued for up to 4 weeks, with dermatomycosis of the feet – within 2 weeks after the elimination of all symptoms.
Side effects
Rare: urticaria, swelling, rash, erythema, burning, itching, irritation at the site of application of the drug.
Drug Interaction
Reduces the effects of polyene antibiotics (amphotericin, nystatin, natamycin, etc.). Propyl ester of para-hydroxybenzoic acid in high concentrations enhances the antifungal action of clotrimazole, dexamethasone decreases.
Clotrimazole activity may be decreased when co-administered with nystatin.
Storage Conditions
In a dry, dark place at 15 25 ° C.
Shelf life
3 years.
Active ingredient
Clotrimazole
Terms and conditions otpuska IZ drugstore
Without prescription
Possible product names
KLOTRIMAZOLE 1% 15ML PP-
KLOTRIMAZOL 1% 15ML. RR
Clotrimazole 1% rd d / nar. approx. 15ml Fl. B M
Clotrimazole RR 1% 15 ML
Clotrimazole rr 1% fl 15ml
Medan Farm, Poland
