Description
Pharmacological action
Agonist of the H1-histamine receptors of the vessels of the inner ear and an antagonist of the H3-histamine receptors of the vestibular nuclei of the central nervous system (CNS).
Does not affect H2-histamine receptors, which improves blood circulation in the vascular strip of the inner ear due to the relaxing effect on the precapillary sphincters of the cochlea and labyrinth.
Relieves symptoms in Meniere’s syndrome and vertigo.
Indications
Meniere’s syndrome, characterized by the following main symptoms:
– dizziness (accompanied by nausea / vomiting)
– hearing loss
– tinnitus
Symptomatic treatment and prevention of vestibular vertigo (various vertigo).
Contraindications
Hypersensitivity to any of the components of the drug. Due to the lack of data on effectiveness and safety: pregnancy and lactation, the age is up to 18 years.
With caution
Betagistin should be prescribed with caution in the treatment of patients with a history of gastric ulcer and duodenal ulcer. Patients with pheochromocytoma and bronchial asthma during the treatment period should be regularly observed by a doctor.
Special instructions
Influence on the ability to drive vehicles and mechanisms
According to the results of clinical trials, the effect of betahistine on the ability to drive a car and other mechanisms is absent or insignificant, since no effects potentially affecting this ability were found.
Composition
1 tablet contains:
active substance:
betahistine dihydrochloride – 16 mg
excipients:
MCC – 303.619 mg
mannitol – 108.081 mg
citric acid monohydrate – 9.4 mg
silicon dioxide colloidal dioxide – 9.4 mg
talcfrd8,5bf11.5 23.5 sflff 23.511 1 tablet contains:
active ingredient:
betahistine dihydrochloride – 16 mg
excipients:
MCC – 303.619 mg
mannitol – 108.081 mg
citric acid monohydrate – 9.4 mg
silicon dioxide colloidal 23 mg – 9 mg – , 5 mg
Side effects of
From the gastrointestinal tract: often (from> 1/100 to <1/10) - nausea and dyspepsia. From the side of the nervous system: often (from> 1/100 to <1/10) - headache. In addition to these effects identified in clinical trials, the following side effects have been reported in post-marketing applications and in the scientific literature (there is insufficient data to estimate their frequency): From the gastrointestinal tract: mild disorders, such as vomiting, pain in the gastrointestinal tract, bloating. As a rule, these effects disappear if you take the drug simultaneously with food or after a dose reduction. From the skin and subcutaneous fat: angioedema, urticaria, pruritus, and rash. On the part of the immune system: hypersensitivity reaction, including anaphylactic reaction reported. Overdose Symptoms: After taking the drug in doses up to 640 mg, mild to moderate symptoms (nausea, drowsiness, abdominal pain) may occur. More serious complications (for example, convulsions, cardiopulmonary complications) can occur when taking high doses of betahistine, especially in combination with other drugs. Treatment: symptomatic. Patients with pheochromocytoma should use the drug under medical supervision. Storage conditions At a temperature not exceeding 25 ° C. Keep out of the reach of children! Expiration 3 years. Deystvuyuschee substances betahistine prescription drug conditions prescription drugstore Appointment Vzrosl m in naznacheniyu Vracha Indications That violations of cerebral circulation, From Meniere’s disease
