Description
Latin name
Fluditec
Release form
Fluditec. Syrup.
Packaging
in 125 ml glass bottles in a carton pack 1 bottle.
Pharmacological action
Mucolytic drug. Mucolytic and expectorant effect is due to the activation of sialic transferase – an enzyme of goblet cells of the bronchial mucosa. It normalizes the quantitative ratio of acidic and neutral sialomucins of bronchial secretion, restores the viscosity and elasticity of mucus, and facilitates its passage. It promotes the regeneration of the mucous membrane, normalizes its structure, activates the activity of the ciliary epithelium, improves mucociliary clearance. Restores the secretion of immunologically active IgA (specific protection) and the number of sulfhydryl groups of mucus components (non-specific protection).
Pharmacokinetics
Absorption
After oral administration of Cmax in blood serum and in the mucous membrane of the respiratory tract is achieved 2-3 hours after oral administration and remains in the mucous membrane for 8 hours.
Excretion of
It is excreted mainly with urine, partially unchanged , partially – in the form of metabolites.
Indications
acute and chronic bronchopulmonary diseases, (tracheitis, bronchitis, tracheobronchitis, bronchial asthma, bronchiectatic disease) and inflammatory diseases of the nasal cavity, nasopharynx, paranasal sinuses and middle ear (rhinitis, adenoiditis, sinusitis, otitis media) accompanied by the formation of a viscous, difficult to secret (sputum, mucus)
preparation for bronchoscopy and / or bronchography.
Contraindications
hypersensitivity to carbocysteine or other components of the drug
peptic ulcer of the stomach and duodenum (in the acute stage)
chronic glomerulonephritis (in the acute stage), cystitis
three years of age up to three years old.
Precautions: chronic glomerulonephritis (history) gastric and duodenal ulcer (history) pregnancy (II III trimester – for syrup 50 mg / ml), lactation period (for syrup 50 mg / ml).
Use during pregnancy and lactation
Contraindicated in the first trimester of pregnancy.
Composition
100 ml contain
carbocysteine 5 g hydrochloride 5 g srdlp 15 g sucrose – 35 g dye Sunny sunset yellow (E110) – 0.0016 g dye patented blue V (E131) – 0.001 g sodium hydroxide – up to pH 6.2 caramel flavor – 0.2 g purified water – up to 100 ml
Dosage and Administration
Inside. Adults 15 ml 3 times a day, preferably 1 hour before meals or 2 hours after eating.
Treatment should not last more than 8-10 days without consulting a doctor (for both dosage forms).
15 ml syrup contains 750 mg carbocysteine.
Side effects of the
Digestive system: nausea, vomiting, diarrhea, epigastric pain, flatulence, gastrointestinal bleeding.
From the side of the central nervous system: dizziness, weakness, malaise.
Allergic reactions: in isolated cases – itching, urticaria, exanthema, angioedema.
Drug Interaction
When used at the same time, Fluditek increases the effectiveness of glucocorticosteroid (mutually) and antibacterial therapy for inflammatory diseases of the upper and lower respiratory tract.
When used at the same time, Fluditek enhances the bronchodilator effect of theophylline.
The activity of carbocysteine is weakened by antitussive and atropine-like agents.
Overdose
Symptoms: gastralgia, nausea, diarrhea.
Treatment: symptomatic therapy.
Storage conditions
The drug should be stored out of the reach of children at a temperature not exceeding 25 ° C.
Expiration
2 years.
Terms
pharmacy leave without a prescription
Dosage form
Dosage form
oral solution
Innotek Internasionaly, France
