Description
Release form
vaginal tablets
Packing
12 pcs.
Pharmacological action
Pharmatex – vaginal contraceptive.
Benzalkonium chloride is both a spermicide and antiseptic. The active substance destroys sperm membranes. The destruction of sperm occurs in two stages: first, the destruction of the flagellum, then rupture of the head, which makes impossibility of fertilization.
The use of Pharmatex significantly reduces the risk of pregnancy, but does not completely eliminate it.
Clinical effectiveness is determined by the corrected Pearl index, which is less than 1 if the drug is used correctly.
In vitro, the drug is active against many sexually transmitted pathogens, especially Neisseria gonorrhoeae, Chlamydia spp., Trichomonas vaginalis, Staphylococcus aureus, Herpes simplex type 2, HIV.
The drug is not active against Mycoplasma spp. and weakly active against Gardnerella vaginalis, Candida albicans, Haemophilus ducreyi and Treponema pallidum.
In vivo, the components of the drug show some activity in the prevention of sexually transmitted diseases, but there is no evidence for this.
The drug does not affect saprophytic vaginal microflora, incl. on the Doderlein wand.
Pharmacokinetics
Benzalkonium chloride is not absorbed by the vaginal mucosa. It is absorbed only on the surface of the walls of the vagina and then excreted with normal physiological secretions or eliminated by simple washing with water.
Indications
radiation injuries and burns of the skin and mucous membranes
colpitis, endocervicitis, – the presence of temporary or absolute contraindications to the use of oral contraceptives or the intrauterine device
– during the period after childbirth and during breastfeeding
– after the abortion
– in the period preceding menopause
– if necessary, occasional protection from pregnancy
– with continued use of oral contraceptives in case of missing or being late in taking the pill.
As an additional local contraception when using the vaginal diaphragm or intrauterine device (especially if some drugs, such as NSAIDs, are taken at the same time).
Contraindications
– the inability to use Pharmatex correctly in people with mental disorders or those who do not allow any interventions on the genitals, and which prevent the use of
contraceptive – to anyone who is unable to understand or agree with this type of contraception
– srdlp and irritation of the mucous membrane of the vagina and uterus
– increased sensitivity to the components of the drug.
Use during pregnancy and lactation
No harmful effects associated with the use of the drug during pregnancy were found. An examination of the teratogenic properties of the final product gave negative results, as did an examination of the teratogenic properties of the active substance itself. In addition, studies have shown that benzalkonium chloride is not absorbed into the blood.
Since it has been proven that the active substance has not penetrated into the blood and breast milk, the use of this spermicide during lactation is not dangerous.
Special instructions
The effectiveness of contraception is associated exclusively with strict observance of the rules for its use: – apply
systematically before each sexual intercourse – enter a capsule (tablet, suppository, tampon, cream) so that the selected dosage form penetrates as deep as possible into the vagina, preferably in the supine position
– wait for the capsule or tablet to completely dissolve in the vagina for at least 10 minutes, the suppository for at least 5 minutes, so that the active substance is completely released
– be sure to introduce a new capsule (tablet, dose of cream, suppository) before each repeated sexual Act
– prohibits the use of soap for the toilet of the genitals 2 hours before sexual intercourse and within 2 hours after sexual intercourse, because soap, even in residual amounts, destroys the active substance of Pharmatex
– immediately after sexual intercourse only the external toilet of the genitals is possible only with clean water or with the help of foaming agent Pharmatex that does not contain soap, which includes benzalkonium chloride. Before doing vaginal irrigation, you should wait 2 hours after
sexual intercourse – with Pharmatex introduced into the vagina, you should not take baths, swim in the sea, pool and water because of the risk of reducing the subsequent contraceptive effect of
– since Pharmatex contains benzalkonium chloride, it is necessary to interrupt its use when the occurrence of any vaginal diseases or their exacerbation
– if there is a need to treat vaginal diseases and / or prescribe any other medication vaginally, it is necessary It is necessary to wait until the end of treatment before resuming (starting) contraception with the help of Pharmatex.
Dosage and administration
Lying on the back, the tablet is injected deep into the vagina no later than 10 minutes before sexual intercourse. The duration of the drug is 3 hours. Be sure to introduce a new tablet before each repeated sexual intercourse. 1 tablet is designed for one sexual intercourse.
Side effects
Allergic reactions: burning, itching, contact dermatitis (if they occur, stop using Pharmatex).
Drug Interactions
Concomitant use with vaginal drugs is not recommended. Any drug introduced into the vagina can inactivate the local spermicidal effect of Pharmatex.
Farmateks is destroyed by soap. Do not do vaginal irrigation before and after sexual contact, because soap, even its traces, destroys the active substance.
Storage conditions
Keep out of the reach and sight of children at temperatures not exceeding 25 ° C.
Expiration
2 years.
active substance
Benzalkonium chloride
lekarstvennaja form
tablets vahynaln e
Innotek Internasionaly, France
