Description
Packaging
7 pcs
Indications
Vaginal candidiasis, acute or relapsing when topical therapy is not applicable to reduce the recurrence rate of vaginal candidiasis (4 or more episodes per year). Candidiasis balanitis when topical therapy is not applicable.
Contraindications
Hypersensitivity to fluconazole, other components of the drug or azole substances, simultaneous administration of terfenadine at a dose of 400 mg / day or more, drugs that increase the QT interval and are metabolized by the CYP3A4 isoenzyme, galactose intolerance, lactase deficiency, lactase deficiency, lactase deficiency age up to 3 years (for capsules).
Caution: liver failure, renal failure, rash on the background of fluconazole in patients with superficial fungal infection and invasive / systemic fungal infections, the simultaneous use of terfenadine and fluconazole at a dose of less than 400 mg / day, potentially proarrhythmic conditions in patients with multiple risk factors.
There is currently no evidence of a link between these congenital malformations and the use of low doses of fluconazole (150 mg once for the treatment of vulvovaginal candidiasis) in the first trimester of pregnancy. During pregnancy, fluconazole should be avoided, except in cases of severe and potentially life-threatening fungal infections, when the expected benefit of treatment outweighs the potential risk to the fetus. During the period of breastfeeding, the appointment of fluconazole is not recommended.
Composition
Each capsule contains:
active substance: fluconazole 50 mg
excipients: lactose 49.708 mg, corn starch 16.5 mg, colloidal silicon dioxide 0.117 mg, magnesium stearate 1.058 mg, sodium lauryl sulfate 0.117 mg capsule shell: titanium dioxide (E171) 4.47%, dye blue patented ( E 131) 0.03%, gelatin up to 100%.
Dosage and Administration
Inside. In acute vaginal candidiasis, candidiasis balanitis, the drug is used once inside at a dose of 150 mg. To reduce the recurrence rate of vaginal candidiasis, the drug can be used in a dose of 150 mg every three days – only 3 doses (on the 1st, 4th and 7th day), then a maintenance dose of 150 mg once a week. A maintenance dose can be used up to 6 months.
Side effects
Frequent: headache, abdominal pain, diarrhea, nausea, vomiting, increased serum activity of aminotransferases (AST, ALT) and alkaline phosphatase, rash.
Storage conditions
Store at a temperature not exceeding 30 ° C, out of the reach of children.
Expiration
3 years
Deystvuyuschee substances
Fluconazole
dosage form
capsules
Indications
That molochnyts
Pfizer, United States
