Description
Release form
Capsules
Pharmacological action of
NOBEN improves metabolic processes in the brain by activating the synthesis of glucose and ATP, improving blood supply and oxygenation of brain tissue, and helps to eliminate lactates. Being an antioxidant, it slows down lipid peroxidation and thereby protects the membranes of neurons and mitochondria from damage.
It has nootropic properties with a psychostimulating effect and neuroprotective effect. From the first days of taking the drug, an antiasthenic, psychostimulating and antidepressant effect is manifested. Nootropic and mnemotropic effects are noted after 20 25 days of treatment.
Pharmacokinetics
Quickly absorbed in the digestive tract, the peak concentration in the blood is reached after 4 hours. T1 / 2 is about 18 hours. It easily penetrates the BBB in significant quantities and is distributed in the brain tissue. No cumulation even with prolonged use. It is metabolized in the liver, excreted in urine and fecal matter.
Indications
Various manifestations of cerebrovascular insufficiency (psycho-organic syndrome) caused by cerebrovascular disorders and age-related involutional changes in the brain cerebroasthenic disorders of the vascular, traumatic, psychogenic (neurasthenia) and combined etiology, manifested in the form of: impaired memory and / or productivity and overall activity, emotional instability, asthenic, asthenodepressive and moderately expressed depressive states, headache, dizziness, tinnitus.
Contraindications
Individual intolerance to Noben, severe renal failure.
Precautions – Pregnancy and lactation.
Special instructions
Impact on the ability to drive a car or other machinery.
It is forbidden to take during work to drivers of vehicles and persons whose profession requires a quick mental and motor reaction, t. K. the study of the effect of the drug on persons driving a car or performing work requiring the speed of psychomotor reactions was not conducted.
Ingredients
Active ingredient:
idebenone 30 mg
Excipients:
lactose monohydrate – 102 mg
MCC 20 mg
potato starch – 39, 4 mg
povidone (low molecular weight polyvinylpyrrolidone medical or plasdon) – 8 mg
magnesium stearate – 0.6 mg
capsule shell:
titanium dioxide – 1.3333%
quinoline yellow ² 0.9197% sundlk yellow 0 srdlp , 0044%
gelatin – up to 100%
Dosage and administration
Inside, 1 capsule (30 mg) 23 times daily after meals, last dose up to 17 hours.
The duration of course therapy is 1.5 – 2 months., Depending on the severity of symptoms, 2 – 3 courses per year are carried out.
Side effects
Allergic reactions, trouble falling asleep, mental agitation, headache, dyspepsia.
Overdose
Symptoms: increased severity of side effects.
Treatment: gastric lavage, intake of activated carbon, symptomatic therapy.
Storage conditions
In a dry, dark place and out of the reach of children, at a temperature no higher than 30 C.
Term hodnosty
3 years
Deystvuyuschee substances
idebenone
Pharmacy terms
Prescription
Dosage form
capsule
Binnofarm, Russia
