Description
Release form
vaginal capsules
Packing
6 pcs.
Pharmacological action
Pharmatex – vaginal contraceptive.
Benzalkonium chloride is both a spermicide and antiseptic. The active substance destroys sperm membranes. The destruction of sperm occurs in two stages: first, the destruction of the flagellum, then rupture of the head, which makes impossibility of fertilization.
The use of Pharmatex significantly reduces the risk of pregnancy, but does not completely eliminate it.
Clinical efficacy is determined by the adjusted Pearl Index, which is less than 1 if the drug is used correctly.
In vitro, the drug is active against many sexually transmitted pathogens, especially Neisseria gonorrhoeae, Chlamydia spp., Trichomonas vaginalis, Staphylococcus aureus, Herpes simplex type 2, HIV.
The drug is not active against Mycoplasma spp. and weakly active against Gardnerella vaginalis, Candida albicans, Haemophilus ducreyi and Treponema pallidum.
In vivo, the components of the drug show some activity in the prevention of sexually transmitted diseases, but there is no evidence for this.
The drug does not affect saprophytic vaginal microflora, incl. on the Doderlein wand.
Pharmacokinetics
Benzalkonium chloride is not absorbed by the vaginal mucosa. It is absorbed only on the surface of the walls of the vagina and then excreted with normal physiological secretions or eliminated by simple washing with water.
Contraindications
– the inability to properly use Pharmatex in persons with mental disorders or persons not allowing any interventions on the genitals, and which hinder the use of the
contraceptive – to anyone who is unable to understand or agree with this type of contraception
–
colpitis – ulceration and irritation of the vaginal mucosa and uterus
– increased sensitivity to the components of the drug.
Use during pregnancy and lactation
No harmful effects associated with the use of the drug during pregnancy were found. An examination of the teratogenic properties of the final product gave negative results, as did an examination of the teratogenic properties of the active substance itself. In addition, studies have shown that benzalkonium chloride is not absorbed into the blood.
Since it has been proven that the active substance has not penetrated into the blood and breast milk, the use of this spermicide during lactation is not dangerous.
Special instructions
The effectiveness of contraception is connected exclusively with strict observance of the rules for its use: – apply
systematically before each sexual intercourse – enter a capsule (tablet, suppository, tampon, cream) so that the selected dosage form penetrates the vagina as deep as possible, preferably in the supine
position – wait until the capsule or tablet has completely dissolved in the vagina for at least 10 minutes, suppository – at least 5 minutes, so that the active substance is completely released
– be sure to introduce a new capsule (tablet, dose of cream, suppository) before each repeated sexual intercourse
– do not use soap for the genitals toilet 2 hours before sexual intercourse and during 2 hours after sexual intercourse, as soap, even in residual amounts, destroys the active substance of Pharmatex
– immediately after sexual intercourse only the external toilet of the genitals is possible only with clean water or with the help of foaming agent Pharmatex that does not contain soap, which includes benzalkonium chloride. Before doing vaginal irrigation, you should wait for 2 hours after
sexual intercourse – with Pharmatex introduced into the vagina, you should not take baths, swim in the sea, swimming pool and water bodies because of the danger of reducing the subsequent contraceptive effect of
– since Pharmatex contains benzalkonium chloride, it is necessary to interrupt its use if any vaginal diseases occur or their exacerbation
– if it becomes necessary to treat vaginal diseases and / or prescribe some or another drug vaginally, it is necessary to wait for the end of treatment before resuming (starting) contraception with the help of Pharmatex.
Dosing and Administration
Lying on your back, the capsule is injected deep into the vagina no later than 10 minutes before sexual intercourse. The duration of the drug is 4 hours. Be sure to introduce a new capsule before each repeated sexual intercourse. 1 capsule is designed for one sexual intercourse.
Side effects
Allergic reactions: burning, itching, contact dermatitis (if they occur, stop using Pharmatex).
Drug Interactions
Concomitant use with vaginal drugs is not recommended. Any drug introduced into the vagina can inactivate the local spermicidal effect of Pharmatex.
Farmateks is destroyed by soap. Do not do vaginal irrigation before and after sexual contact, because soap, even its traces, destroys the active substance.
Storage Conditions
Keep out of the reach and sight of children at temperatures not exceeding 25 ° C.
Expiration
2 years.
active substance
Benzalkonium chloride
ez prescription
dosage form
capsule vaginal
Prescribing
For women of childbearing age
Indications
Indications
Indications for reflex ofagit, heartburn, gastro enteritis, gastric ulcer and 12 duodenal ulcer,Ia
Indications
For contraception
Innotek Internasionaly, France
