Description
Latin name
Relenza
Release form
Powder for inhalation.
20 g
packaging
Pharmacological action
Relenza – an antiviral agent.
Highly selective inhibits neuraminidase, a surface enzyme of the influenza virus, including all known subtypes of influenza A virus neuraminidase, blocks the replication of influenza A and B. viruses
Prevents the release of new viral particles from infected cells, the interaction of viruses with the surface of the airway epithelial cells and their infection.
Indications
Prevention and treatment of influenza A and B in adults and children older than 5 years.
Contraindications
Hypersensitivity to the components of the drug.
Use during pregnancy and lactation
Contraindicated in the first trimester of pregnancy, in the second and third trimesters it is possible if the expected effect of therapy exceeds the potential risk to the fetus. At the time of treatment should stop breastfeeding.
Composition
1 dose contains 5 mg zanamivir, as well as lactose as a filler.
Dosage and administration of
Inhalation using a special device, Relenza Diskhaler.
Treatment: 2 inhalations (5 mg x 2) 2 times a day for 5 days (maximum daily dose – 20 mg), treatment is recommended to begin within the first two days of the disease.
Prevention: 2 inhalations (5 mg x 2) once a day for 10 days (maximum daily dose is 10 mg).
Side effects
Very rarely – bronchospasm, shortness of breath, allergic reactions (including rash, urticaria, swelling of the face and mucous membrane of the oropharynx).
Drug Interaction
Do not combine with other inhalation drugs (including bronchodilators).
Overdose
Accidental overdose is unlikely due to dosage administration, route of administration, and low bioavailability of the drug.
No side effects were reported with inhalation administration of 64 mg / day (more than 3 times the recommended daily dose). They are also not registered with parenteral administration of the drug Relenza in a dose of 1. 2 g / day within 5 days.
Storage conditions
At a temperature not exceeding 30 ° C.
Expiration
5 years.
Deystvuyuschee substances
zanamivir
Terms of delivery from
pharmacies Prescription
dosage form
dosage form
powder for inhalation
GlaxoSmithKline, UK
