Description
Latin name
Selang
Release form
nasal drops.
Packaging
Nasal drops, 3 ml each, in a glass bottle, sealed with a plastic pipette stopper, or in a glass bottle, sealed with a plastic screw cap with the included pipette with a cap. Each bottle with instructions for use is packed in a pack of cardboard.
Pharmacological action
Pharmacotherapeutic group: anxiolytic agent (tranquilizer).
ATX code: N05BX
Pharmacological action of
Pharmacodynamics
Selank ® is a synthesized analogue of the endogenous taftcine peptide and has an original mechanism of neurospecific action on the central nervous system.
Selank ® has an anti-anxiety effect with an antidepressant effect and an anti-asthenic effect.
Relieves symptoms of anxiety, anxiety, fear, apathy, depression, and asthenia.
Has a positive effect on cognitive functions, improves memory, speech, increases attention, activates learning processes, in particular, memorization, analysis and reproduction of information. Normalizes psychomotor reactions.
During stress, Selank ® eliminates emotionally-negative stress and stimulates the development of adaptive behavior aimed at achieving a useful result.
Pharmacokinetics
Selank ® is administered intranasally (nasal drops). The absolute bioavailability of Selank ® when administered to the nasal mucosa is 92.8%. The drug is rapidly absorbed from the nasal mucosa and after 30 seconds it is detected in the blood plasma, and then quickly distributed to various organs and tissues. It penetrates the brain tissue. The concentration in the blood plasma progressively decreases over 5-5.5 minutes. Neither unchanged drug nor metabolites are detected in daily urine, which is due to the rapid degradation of Selank ® under the influence of tissue peptidases.
Indications
Anxiety:
² Ñ unmotivated anxiety, anxiety
² Ñ panic attacks
² Ñ neurasthenia
² Ñ asthenia
² Ñ instability of mood
² Ñ sleep disturbance, lack of decision, lack of confidence, lack of confidence, lack of confidence, lack of will, ² Ñ Insecurity in communication
² Ñ Disorders of adaptation
Prevention and treatment of stress disorders.
Contraindications
Individual intolerance to the drug.
Pregnancy, breastfeeding (studies of efficacy and safety have not been conducted).
Children under 18 years of age (efficacy and safety studies have not been conducted).
Use during pregnancy and lactation
Pregnancy
Since controlled studies of the use of the drug Selank ® in pregnant women have not been conducted, it should not be used during pregnancy.
Breastfeeding period
If you need to use the drug during lactation, you should refrain from breastfeeding.
Composition
Composition per 1 ml: Active ingredient: Selanka ® in terms of 100% substance (threonyl-lysylprolyl-arginyl-prolyl-glycyl-proline diacetate) – 1.5 mg.
Excipients: methyl parahydroxybenzoate (nipagin) – 1 mg, purified water to 1 ml.
Dosage and administration
Selank ® is administered intranasally using a vial sealed with a plastic screw cap or a dropper cap.
If the bottle is sealed with a plastic screw cap, at the first use remove the plastic screw cap and replace it with the supplied pipette with a cap.
Pipette the drug.
Squeeze out the required number of drops of the drug on a clean mucous membrane of the nasal passage, and then hold the nostril with your finger for a short time.
If the bottle is sealed with a dropper cap, carefully cut off the tip of the pipette, tightly close the pipette with a cap. Turn over the bottle before use, so that the liquid fills the entire space of the pipette. Remove the cap. Squeeze out the required number of drops of the drug on a clean mucous membrane of the nasal passage, and then hold the nostril with your finger for a short time.
The drug is instilled into the nasal passages in a sitting position with the head slightly tilted or tilted to one side, after which each nostril is clamped with a finger for a short time.
The effectiveness of absorption may be reduced in the presence of increased secretions by the nasal mucosa, so it is recommended to clean the nasal passage before use (instillation).
Dose: 2 drops in each nasal passage 3 times a day.
The duration of the course of the drug is 14 days. If necessary, the course of treatment can be repeated after 1-3 weeks, after consulting a doctor.
Use the drug only according to the method of use and at the doses indicated in the instructions. If necessary, please consult your doctor before using the medicine.
Side effects
With increased sensitivity to the perception of smell and taste, if the drug gets from the nasal cavity to the mucous membrane of the pharynx, unpleasant taste sensations may appear. Perhaps the development of allergic reactions with individual intolerance.
If any of the side effects indicated in the instructions are aggravated, or you notice any other side effects not listed in the instructions, inform your doctor.
The drug interaction of
Selank ® has no effect on the effects of drugs, depressing and stimulating the central nervous system – haloperidol, pentobarbital, hexobarbital, analeptics.
Selank ® can be combined with any psycho and neuroactive therapy.
Selank ® is safe when combined with ethanol-containing agents.
If you are taking other medicines (including over-the-counter medications), consult your doctor before using Selanc ®.
Overdose
No cases of overdose have been reported with the use of Selank ®.
Storage conditions
Store in a dark place at a temperature not exceeding 10C.
Do not freeze. Store the opened bottle at a temperature not exceeding 25 ° C for no more than 15 days.
Keep out of the reach of children.
Expiration
2 years.
Deystvuyuschee substances
Treonyl-Lyzyl-shed-Arhynyl-shed-Hlytsyl-proline
pharmacy terms and conditions Over-the-counter
dosage form
dosage form
nasal drops
Peptogen, Russia
