Description
Topical release
solution for local use
Packaging
bottle with sprayer 150 ml
Pharmacological action
Miramistin ® has a wide spectrum of antimicrobial activity, including hospital strains that are resistant to antibiotics.
The drug has a pronounced bactericidal effect against gram-positive (Staphylococcus spp., Streptococcus spp., Streptococcus pneumoniae and others), gram-negative (Pseudomonas aeruginosa, Escherichia coli, Klebsiella spp. and others), aerobic bacteria and ana and microbial associations, including hospital strains with antibiotic resistance.
Has an antifungal effect on the ascomycetes of the genus Aspergillus and the genus Penicillium, yeast (Rhodotorula rubra, Torulopsis gabrata, etc.) and yeast-like fungi (Candida albicans, Candida tropicalis, Candida krusei, Pityrosporum orbiculare (Malassezia furfur), etc.), dermatophytes (Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton verrucosum, Trichophyton schoenleini, Trichophyton violacent, Epidermophyton Kaufman-Wolf, Epidermophyton floccosumum, Microspospum, Microspospum, Microsp as well as other pathogenic fungi, in the form of monocultures and microbial associations, including fungal microflora with resistance to chemotherapeutic drugs.
It has an antiviral effect, is active against complex viruses (herpes viruses, human immunodeficiency virus, etc.).
Miramistin ® acts on pathogens of sexually transmitted diseases (Chlamydia spp., Treponema spp., Trichomonas vaginalis, Neisseria gonorrhoeae, etc.).
Effectively prevents infection of wounds and burns. It activates the regeneration processes. It stimulates protective reactions at the site of application, by activating the absorbing and digesting functions of phagocytes, and potentiates the activity of the monocyte-macrophage system. It has a pronounced hyperosmolar activity, as a result of which it stops wound and perifocal inflammation, absorbs purulent exudate, contributing to the formation of a dry scab. Does not damage granulation and viable skin cells, does not inhibit edge epithelization.
Not locally irritating and allergenic.
Pharmacokinetics
When applied topically, miramistin is not able to be absorbed through the skin and mucous membranes.
Indications
Surgery, traumatology: prevention of suppuration and treatment of purulent wounds. Treatment of purulent-inflammatory processes of the musculoskeletal system.
Obstetrics, gynecology: prevention and treatment of suppuration of postpartum injuries, perineal and vaginal wounds, postpartum infections, inflammatory diseases (vulvovaginitis, endometritis).
Combustiology: treatment of superficial and deep burns of the II and IIIA degrees, preparation of burn wounds for dermatoplasty.
Dermatology, venereology: treatment and prevention of pyoderma and dermatomycosis, candidiasis of the skin and mucous membranes, foot mycoses.
Individual prevention of sexually transmitted diseases (including syphilis, gonorrhea, chlamydia, trichomoniasis, genital herpes, genital candidiasis).
Urology: complex treatment of acute and chronic urethritis and urethroprostatitis of specific (chlamydia, trichomoniasis, gonorrhea) and non-specific nature.
Dentistry: treatment and prevention of infectious and inflammatory diseases of the oral cavity: stomatitis, gingivitis, periodontitis, periodontitis. Hygienic treatment of removable dentures.
Otorhinolaryngology: complex treatment of acute and chronic otitis media, sinusitis, tonsillitis, laryngitis, pharyngitis.
In children aged 3 to 14 years, it is used for the complex treatment of acute pharyngitis and / or exacerbation of chronic tonsillitis.
Contraindications
Individual intolerance to the drug.
Use during pregnancy and lactation
Possible
Dosage and Administration
Topically. The drug is ready for use.
Directions for use with spray bottle packaging:
1. Remove the cap from the vial.
2. Remove the supplied spray nozzle from its protective packaging.
3. Attach the spray nozzle to the bottle.
4. Activate the spray nozzle by pressing again.
Surgery, Traumatology, Combustiology. For prophylactic and therapeutic purposes, they irrigate the surface of wounds and burns, loosely tampon wounds and fistulous passages, and fix gauze swabs moistened with the drug. The treatment procedure is repeated 2-3 times a day for 3-5 days. A highly effective method of active drainage of wounds and cavities with a daily flow rate of up to 1 liter of the drug.
Obstetrics, gynecology. In order to prevent postpartum infection, it is used in the form of vaginal irrigation before childbirth (57 days), in childbirth after each vaginal examination and in the postpartum period, 50 ml of the drug in the form of a tampon with an exposure of 2 hours for 5 days. During the delivery of women by cesarean section, immediately before the operation the vagina is treated, during the operation – the uterine cavity and incision on it, and in the postoperative period, tampons moistened with the drug are administered, into the vagina with an exposure of 2 hours for 7 days. Treatment of inflammatory diseases is carried out by the course for 2 weeks by intravaginal administration of tampons with the drug, as well as by the method of drug electrophoresis.
Venereology. For the prevention of sexually transmitted diseases, the drug is effective if it is used no later than 2 hours after sexual intercourse. Using the urological applicator, insert the contents of the vial into the urethra for 2-3 minutes: for men – 2-3 ml, for women – 1-2 ml and in the vagina – 5-10 ml. To process the skin of the inner surfaces of the hips, pubis, genitals After the procedure, it is recommended not to urinate for 2 hours.
Urology. In the complex treatment of urethritis and urethroprostatitis, 2-3 ml of the drug is injected 1-2 times a day into the urethra, the course is 10 days.
Otorhinolaryngology. With purulent sinusitis – during a puncture, the maxillary sinus is washed with a sufficient amount of the drug.
Tonsillitis, pharyngitis and laryngitis are treated with gargling and / or irrigation using a spray nozzle, 3-4 times pressing 3-4 times a day. The amount of the drug for 1 rinse is 10-15 ml.
In children. In acute pharyngitis and / or exacerbation of chronic tonsillitis, pharynx is irrigated using a spray nozzle. Children aged 36 years 3-5 ml per irrigation (a single press on the nozzle head) 3-4 times a day 714 years 57 ml per irrigation (a double press) 3-4 times per day older than 14 years – 10-15 ml per irrigation (3-4 times pressing) 3-4 times a day. The duration of therapy is from 4 to 10 days, depending on the timing of the onset of remission.
Dentistry. With stomatitis, gingivitis, periodontitis, it is recommended to rinse the oral cavity with 10-15 ml of the drug 3-4 times a day.
Side effects
In some cases, at the injection site, you may experience a slight burning sensation that passes on its own after 15 20 s and does not require discontinuation of the drug.
Allergic reactions.
Drug Interactions
With simultaneous use with antibiotics, an increase in their antibacterial and antifungal properties was noted.
Storage conditions
At a temperature not exceeding 25 ° C.
Term hodnosty
3 years
Dosage form
solution for topical application
Prescription vrdlkp ormyaschym mothers to children, Vzrosl m
Possible product names
Miramistin solution for local application 0.01% bottle with spray 150 ml
Miramistin bottle with spray 0.01%, 150 ml
Infamed, Russia
