Description
Packing
21 pcs.
Pharmacological action
An analogue of the hormone of the pineal gland (pineal gland) melatonin has an adaptogenic, sedative, hypnotic effect. Normalizes circadian rhythms. Increases the concentration of GABA and serotonin in the midbrain and hypothalamus, changes the activity of pyridoxalkinase involved in the synthesis of GABA, dopamine and serotonin. Regulates the sleep-wake cycle, diurnal changes in locomotor activity and body temperature, positively affects the intellectual-mnestic functions of the brain, on the emotional and personal sphere. Promotes the organization of biological rhythm and the normalization of night sleep. Improves the quality of sleep, reduces the frequency of attacks of headaches, dizziness, and improves mood. It speeds up falling asleep, reduces the number of night awakenings, improves well-being after morning awakening, does not cause a feeling of lethargy, fatigue and fatigue upon waking up. Makes dreams more vivid and emotionally saturated. Adapts the body to a quick change of time zones, reduces stress reactions, regulates neuroendocrine functions. It exhibits immunostimulating and antioxidant properties. It inhibits the secretion of gonadotropins, to a lesser extent – other hormones of the adenohypophysis – corticotropin, TSH, STH. The secretion of melatonin is subordinated to the circadian rhythm, which determines the rhythm of gonadotropic effects and sexual function. The synthesis and secretion of melatonin depends on the light – an excess of light inhibits its formation, a decrease in light increases the synthesis and secretion of the hormone. In humans, nighttime hours account for 70% of the daily production of melatonin. Under the influence of melatonin, the content of the inhibitory mediator GABA – in the central nervous system and serotonin – in the midbrain and hypothalamus increases.
Contraindications
Hypersensitivity, allergic diseases, autoimmune diseases, lymphogranulomatosis, leukemia, lymphoma, myeloma, epilepsy, diabetes mellitus, chronic renal failure, pregnancy, lactation.
Pregnancy and lactation
Contraindicated
Special instructions
Inform women who wish to become pregnant, the presence of a weak contraceptive effect in the drug. Avoid bright lighting. During the treatment period, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require an increased concentration of attention and speed of psychomotor reactions.
Composition
1 tab. contains melatonin 2 mg
Dosage and administration
Cycadine is taken orally, 1.5-3 mg once a day, 30-40 minutes before bedtime. The maximum daily dose is 6 mg.
Side effects
Allergic reactions, headache, nausea, vomiting, diarrhea, morning drowsiness, edema.
Drug interaction
Incompatible with MAO inhibitors, corticosteroids, cyclosporine. Enhances the effect of (mutually) drugs, depressing the central nervous system, and beta-blockers. Concomitant use with NSAIDs is not recommended.
Storage conditions
The product should be stored out of the reach of children at a temperature not exceeding 25 ° C.
Term hodnosty
2 years
Terms leave through pharmacies
In retseptu
Dosage form
tablet prolong.
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