Description
Latin name
Mydocalm
Release form
Film-coated tablets.
packaging 30 pcs
Pharmacological action
Midokalm – central muscle relaxant.
Reduces pathologically increased muscle tone, muscle stiffness, improves voluntary active movements.
The mechanism of action is associated with a regulatory effect on the caudal part of the reticular formation, suppression of pathologically increased spinal reflex activity, and effects on peripheral nerve endings.
Indications
organic and degenerative neurological diseases, accompanied by an increase in the striated muscle tone (pyramidal tract injuries, multiple sclerosis, myelopathy, encephalomyelitis, consequences of stroke, muscle contractures, muscle stiffness, spinal automatism)
muscle hypertonia
muscle spasms
cerebral artery disease dystonia (including in childhood).
Contraindications
psychosis
epilepsy
Parkinson’s disease
hypersensitivity to the drug Midokalm.
Use during pregnancy and lactation
Use during pregnancy, especially in the first trimester, and during lactation (breastfeeding) is possible in cases where the expected benefits of therapy for the mother outweigh the potential risk to the fetus or infant.
Composition
1 tablet contains:
Actives:
tolperizona hydrochloride 150 mg,
Excipients:
lactose,
citric acid monohydrate,
silica colloidal anhydrous,
stearin,
talc,
microcrystalline cellulose,
cornstarch,
titanium dioxide (E171),
dye (E129 or E172).
Film sheath:
silicon dioxide colloidal dioxide
titanium dioxide (E171 – 77891)
lactose monohydrate
macrogol 6000
hypromellose
Dosage and administration
Inside, after meals, without chewing, washed down with a little water.
Adults and children from 14 years of age – usually starting with 50 mg 2-3 times a day, gradually increasing the dose to 150 mg 2-3 times a day.
For children from 3 to 6 years of age – Midokalm is prescribed orally in a daily dose of 5 mg / kg 7-14 years – 2-4 mg / kg (in 3 divided doses throughout the day).
Side effects
muscle weakness,
headache,
arterial hypotension,
nausea,
vomiting,
abdominal discomfort.
Side effects usually go away with a reduced dose.
In rare cases, allergic reactions (skin itching, erythema, urticaria, angioedema, anaphylactic shock, bronchospasm) are encountered.
No drug interaction
There are no drug interaction data limiting the use of Midocalm.
Although tolperisone has an effect on the CNS, it does not cause sedation and can therefore be used in combination with sedatives, hypnotics and ethanol-containing drugs.
Does not change the effect of ethanol on the CNS.
Overdose
There is insufficient data on the overdose of the drug Midocalm.
Storage conditions
Store at room temperature.
Expiration
3 years.
dosage form
dosage form
tablets
