glucosamine sulfate – Don tablets 750 mg 60 pcs

$35.00

Description

Latin name

Dona

Release form

Oblong oval-coated tablets, white-coated, 750 mg. On the cross section, two layers are visible – the outer white, the inner – white with a yellowish or brownish tint.

60 tablets in a plastic bottle with a snap-on lid, together with instructions for use, are placed in a cardboard box.

Pharmacological action

Pharmacodynamics

DONA has anti-inflammatory and analgesic effects, replenishes endogenous glucosamine deficiency, stimulates the synthesis of proteoglycans and hyaluronic acid, the synovial fluid and the cell penetrate the permeability cartilage. It promotes the fixation of sulfur during the synthesis of chondroitin sulfuric acid, facilitates the normal deposition of calcium in bone tissue, inhibits the development of degenerative processes in the joints, restores their function, reducing joint pain.

Pharmacokinetics

Absorption in the gastrointestinal tract 90%, bioavailability 25%, half-life 70 hours.

Indications

Osteoarthrosis of the peripheral joints and spine, osteochondrosis.

Contraindications

Individual hypersensitivity to the active substance and other components of the drug, severe chronic renal failure. It is not recommended to prescribe the drug during pregnancy and lactation, as well as in childhood (up to 12 years) due to the lack of scientific clinical data in this category of patients.

Use during pregnancy and lactation

It is not recommended to prescribe the drug during pregnancy and lactation due to the lack of scientific clinical data in this category of patients.

Special instructions

When using the drug in patients with impaired glucose tolerance, with severe hepatic and renal failure, medical supervision is necessary.

Composition

One tablet contains:

active substance: glucosamine sodium sulfate chloride 942 mg (equivalent to glucosamine sulfate 750 mg and sodium chloride 192 mg)

excipients: microcrystalline cellulose 68 mg, povidone K 25 (polyvinylpyrrolidone K 25) 45 mg, croscarmellose sodium 20 mg, macrogol 6000 (polyethylene glycol 6000) 15 mg, magnesium stearate 8.50 mg, talc 1.50 mg

shell: methacrylic acid and methyl methacrylate copolymer [1: 1] (Eudragit L 12.5) 1 0 mg ground titanium dioxide 11.50 mg, talc 10.55 mg, methyl methacrylate, trimethylammonioethyl methacrylate chloride and ethyl acrylate copolymer [2: 0.2: 1] (Eudragit RL 30 D) 4.50 mg, triacetin (glycerol triacetate) 0.90 mg, macrogol 6000 (polyethylene glycol 6000) 0.55 mg.

Dosage and Administration

Inside.

1 tablet 750 mg is taken orally 2 times a day, preferably with meals, with a glass of water. Symptomatic effect occurs 2-3 weeks after the use of the drug. The minimum course of therapy is 4-6 weeks.

If necessary, repeat the treatment at intervals of 2 months. The duration and treatment regimen is prescribed by the attending physician.

Precautions for use:

Caution should be exercised in patients who are allergic to seafood (shrimp, shellfish). The drug contains 75.5 mg of sodium per tablet, which should be considered in patients who follow a controlled sodium diet. Use with caution in bronchial asthma and diabetes.

Side effects

Tolerance to the drug is good, in some cases possible: gastralgia, flatulence, nausea, diarrhea, constipation, headache, drowsiness, allergic reactions – erythema, urticaria, itching.

Drug Interactions

Compatible with non-steroidal anti-inflammatory drugs, paracetamol and glucocorticosteroids. Increases the absorption of tetracyclines, reduces semi-synthetic penicillins, chloramphenicol enhances the effect of coumarin anticoagulants.

Overdose

Overdose is unknown. Treatment: gastric lavage, symptomatic therapy.

Storage Conditions

Do not store above 25 C. Store in places out of reach of children.

Shelf life

3 years. Do not use after the expiration date printed on the package.

Deystvuyushtee substance

Glucosamine sulyfat

tablet dosage form of tablets

Possible product names

DONA 0.75 N60 TABLE P / O

DONA 750MG. No. 60 TAB. P / O

Dona tab p / p / o 750mg N60

DONA TAB. P.P.O. 750MG No. 60

Dona tab / o 0.75 No. 60

Rottafarm, Italy