Description
Packing
1 pc
Pharmacological action
Candide – a wide spectrum antifungal.
The antimycotic effect of the active substance, clotrimazole (an imidazole derivative), is associated with impaired synthesis of ergosterol, which is part of the cell membrane of fungi, which changes the membrane permeability and causes subsequent cell lysis.
It acts fungistatically in small concentrations, fungicidal in large concentrations, and not only on proliferating cells.
In fungicidal concentrations, it interacts with mitochondrial and peroxidase enzymes, As a result, there is an increase in the concentration of hydrogen peroxide to a toxic level, which also contributes to the destruction of fungal cells.
Effective against dermatophytes, yeast-like and mold fungi, as well as the causative agent of colorful lichen (Pityriasis versicolor) and the pathogen of erythrasma.
It has antimicrobial activity against gram-positive (staphylococci, streptococci) and gram-negative bacteria (Bacteroides, Gardnerella vaginalis), as well as against Trichomonas vaginalis.
Indications of
genital infections caused by yeast-like fungi of the genus Candida and / or Trichomonas vaginalis (candidiasis vulvovaginitis, trichomoniasis)
genital superinfection caused by microorganisms sensitive to clotrimazolumiduration sordl.
Contraindications
hypersensitivity to clotrimazole or
excipients I trimester of pregnancy
menstruation period.
Precautions: period of breastfeeding.
Composition
Tablets vaginal
1 tablet contains:
Active substance:
Clotrimazole 500 mg
Excipients:
Lactose
Starch
carboxymethyl starch sodium
Talc purified
Magnesium stearate
Silicon dioxide colloid
Methyl parahydroxybenzoate (methyl paraben)
Propyl (propylparaben)
Dosage and Administration
Topically. It is administered intravaginally, deeply, in the supine position with slightly bent legs.
500 mg once daily (in the evening). A second course of treatment is possible after consulting a doctor.
For the rehabilitation of the birth canal, a single administration of 1 tablet is recommended.
Side effects
Itching, burning and swelling of the vaginal mucosa, vaginal discharge, headache, gastralgia, rapid urination, intercurrent cystitis, burning sensation in the penis of the sexual partner, pain during intercourse.
Overdose
The use of the drug in elevated doses does not cause any reactions and conditions that are life-threatening.
Symptoms (in case of unintended use of the drug by mouth): anorexia, nausea, vomiting, gastralgia, impaired liver function rarely – drowsiness, hallucinations, pollakiuria, skin allergic reactions.
Treatment: the appointment of activated carbon, if necessary – symptomatic therapy there is no specific antidote.
Storage conditions
In a dry, dark place at a temperature of no higher than 25 ° C.
Expiration
4 years.
Dispensing conditions from
pharmacies No prescription
Form of Treatment
tablets vaginalyn e
Indications
From thrush, From inflammation of the female genital organs
Possible product names
CANDID 0.5 N1 TAG VAG / WITH APPLICATOR /
Candid 500mg Tab. vaginal (with applicator) X1 (R)
CANDID TAB. VAGIN. WITH APPLICATOR 500MG No. 1
Candide vaginal tablets 500 mg 1 pc.
Candide vaginal tablets 500 mg, 1 pc.
Glenmark Pharmaceuticals Ltd., India
