Description
Release form
effervescent tablets.
Packaging
1 paper laminated strip 2 tablets. In a cardboard bundle of 6 strips.
Pharmacological action
analgesic (non-narcotic)
antiplatelet
antipyretic.
Indications
Symptomatic treatment:
Headache.
Toothache.
Sore throat.
Muscle and joint pain.
Pain during menstruation. Back pain.
Mild arthritis pain.
Elevated body temperature in colds and other infectious and inflammatory diseases (in adults and children over 15 years of age).
Contraindications
Hypersensitivity to acetylsalicylic acid and other NSAIDs.
Erosive-ulcerative lesions of the gastrointestinal tract (in the acute phase).
Gastrointestinal bleeding.
Asthma caused by salicylates or other NSAIDs combined with nasal polyps.
The combined use of methotrexate at a dose of 15 mg per week or more.
Severe impaired liver or kidney function.
Hemorrhagic diathesis.
Hemophilia, thrombocytopenia.
Deficiency of glucose-6-phosphate dehydrogenase.
Pregnancy (I and III trimester).
Breastfeeding period.
Children’s age (up to 15 years).
Caution is advised in the following cases:
With concomitant anticoagulant therapy.
Gout.
Peptic ulcer of the stomach and / or duodenum (history).
Erosive gastritis.
Tendency to gastrointestinal bleeding.
Hypoprothrombinemia.
Hypovitaminosis K.
anemia.
Conditions predisposing to fluid retention in the body (including impaired heart function, arterial hypertension).
Thyrotoxicosis.
Use during pregnancy and lactation
In the second trimester of pregnancy, a single dose of the drug in recommended doses is possible only if if the expected benefit to the mother will exceed the potential risk to the fetus.
If you need to use the drug during lactation, breastfeeding should be discontinued.
Special instructions
Acetylsalicylic acid reduces the excretion of uric acid from the body, which can cause an acute attack of gout in susceptible patients.
With prolonged use of the drug, a general blood test and analysis of feces for occult blood should be done periodically, and the functional state of the liver should be monitored.
Since acetylsalicylic acid slows down blood coagulation, the patient, if he has surgery, must warn the doctor in advance about taking the drug.
Ethanol (an increased risk of gastrointestinal bleeding) should be discontinued during treatment.
Pediatric use
The drug is not prescribed as an antipyretic to children under 15 years old with acute respiratory infections caused by viral infections, due to the risk of Reye ² ¢s syndrome (encephalopathy and acute fatty liver disease with acute development of liver failure).
Ingredients
1 tablet for the preparation of an effervescent drink contains:
Active ingredients
Acetylsalicylic acid – 500 mg
Excipients
Microcrystalline cellulose,
corn starch.
Dosage and administration of
Inside, after meals, after dissolving the tablet in a glass of water.
A single dose is 1 2 effervescent tablets. The maximum single dose is 2 effervescent tablets. The maximum daily dose should not exceed 6 tablets.
The intervals between doses of the drug should be at least 4 hours.
The duration of treatment without consulting a doctor should not exceed 5 days when prescribed as an anesthetic and 3 days as an antipyretic.
Side effects
From the gastrointestinal tract
Abdominal pain, nausea, vomiting, overt (black stools, bloody vomiting) or latent signs of gastrointestinal bleeding, which can lead to iron deficiency anemia, erosive and ulcerative lesions, including with perforation, of the gastrointestinal tract.
Rarely – impaired liver function (increased hepatic transaminases, AST, ALT).
From the central nervous system
Dizziness, tinnitus (usually signs of an overdose).
From the hemopoietic system
Hemorrhagic syndrome, thrombocytopenia.
From the urinary system
When used in high doses – hyperoxaluria and the formation of urinary stones from calcium oxalate, damage to the glomerular apparatus of the kidneys.
Allergic reactions
Skin rash, anaphylactic reactions, bronchospasm, Quincke edema.
If you experience these symptoms, it is recommended that you stop taking the drug and consult your doctor immediately.
Drug interactions
Strengthening the toxicity of
drugs Increases the toxicity of methotrexate, the effects of narcotic analgesics, other NSAIDs, oral hypoglycemic drugs, heparin, indirect anticoagulants, thrombolytic and thromin thrombase aggregation inhibitors (thromin thrombazides), reserpine.
Reduces the effects of uricosuric drugs
Reduces the effects of uricosuric drugs (benzbromarone, sulfinpyrazone), antihypertensive drugs and diuretics (spironolactone, furosemide).
Increases the plasma concentration of the following drugs
Increases the concentration of digoxin, barbiturates and lithium preparations in the blood plasma.
Enhances the damaging effect on the mucous membrane of the gastrointestinal tract of drugs
Glucocorticosteroids, alcohol and alcohol-containing drugs increase the damaging effect on the mucous membrane of the gastrointestinal tract, increase the risk of gastrointestinal bleeding.
Decreased absorption of acetylsalicylic acid
Antacids containing magnesium and / or aluminum hydroxide slow down and impair the absorption of acetylsalicylic acid.
Overdose
Symptoms: CNS excitation, Dizziness, severe headache, decreased hearing acuity, visual impairment, nausea, vomiting, increased breathing.
In the late stage of poisoning: drowsiness, convulsions, anuria, consciousness decay up to coma, respiratory failure, disturbances of water-electrolyte exchange.
Treatment: You should consult a doctor. Treatment should be carried out in a specialized department. For signs of poisoning – induction of vomiting or gastric lavage, the appointment of activated charcoal and laxative.
Storage Conditions
Store in a dry, dark place at temperatures below 25 ° C.
Keep out of the reach and sight of children. Do not use after the expiry date.
Shelf life
3 years.
Deystvuyushtee substance
Atsetilsalitsilovaya Chisloth
dosage form
tablets soluble
Prescribing
Prescribing
For children over 15 years of age, Pregnant women only II trimester as prescribed by the doctor, For adults
