Description
Latin name
RAUNATINE
Release form
Tablets.
packaging 50 pcs
Pharmacological action
Rauwolfia alkaloids have antihypertensive and antiarrhythmic effects.
Sedative effect is less pronounced than that of reserpine, but they are practically not inferior to reserpine in hypotensive effect, and in some cases they are better tolerated.
The antihypertensive effect of Raunatin develops more slowly than that of reserpine.
Indications
Mild to moderate arterial hypertension.
Contraindications
arterial hypotension
depression
coronary circulatory insufficiency
organic myocardial lesions
aortic malformations
peptic ulcer disease duodenal ulcer srdlerkrpfc nephr
Use during pregnancy and lactation
Contraindicated in pregnancy (III trimester), during lactation.
Composition
Active ingredient:
rauwolfia alkaloids 2 mg.
Dosage and administration of
Raunatin is taken orally after a meal. On the 1st day, take 1 tablet (2 mg – in terms of the amount of alkaloids) at night on the 2nd day – 1 tablet 2 times a day, on the 3rd day – 3 tablets, gradually increasing the total dose to 4- 6 tablets per day.
After achieving a therapeutic effect (after 10-14 days), the dose is gradually reduced to 1-2 tablets per day.
Side effects
Possible swelling of the nasal mucosa, increased sweating, asthenia, cardialgia, bradycardia, depression, decreased libido.
Drug Interaction
Caution is prescribed with quinidine, guanethidine, cardiac glycosides, beta-blockers (risk of increased severity of negative chrono- and dromotropic action).
Overdose
Symptoms: sweating, general weakness and severe hypotension. In severe cases, after a short period of euphoria, drowsiness, depression, hypodynamia, phenomena of marked parkinsonism, loss of consciousness, coma develop.
Treatment: cancellation of the drug, gastric lavage, intake of activated carbon. Forced diuresis is shown.
With a marked decrease in blood pressure, with the collapse of the patient to lay with his legs up. If necessary, intravenous administration of
of reopolyglukin or mesaton with the addition of angiotensinamide or 2% solution of norepinephrine hydrotartrate is indicated. Adrenomimetic agents are prescribed with great caution because of the risk of pulmonary edema. A 10% solution of caffeine sodium benzoate is administered subcutaneously. The presence of sharp respiratory depression or its delay require suction of mucus from the respiratory tract, intubation and conducting artificial ventilation of the lungs, oxygen therapy.
There are no specific antidotes for poisoning with raunatin and other preparations of rauwolfia.
Storage conditions
In the dark place at a temperature of no higher than 20 ° C.
Expiration
3 years.
extract Active ingredient
Rauwolfia alkaloids
pharmacy terms for prescription
dosage form
dosage form
tablets
Vifiteh, Russia
