Description
Release form
Shredded vegetable raw materials
Packing
Pack of 50 g.
Pharmacological action of
St. John’s wort has an astringent and anti-inflammatory effect due to the contained flavonoids, azulene and essential oils, as well as a mild antidepressant, sedative and anxiolytic effect.
The antidepressant effect is due to the ability to inhibit the reuptake of serotonin, norepinephrine and dopamine.
Indications
Symptomatic and reactive depression, anxiety, sleep disturbances.
As an additional remedy for endogenous depression (especially in menopause), as well as for diseases of the lungs, stomach, intestines, gall bladder.
Outwardly: as an additional agent for joint and muscle pain, as well as hemorrhages and herpes zoster for disinfection of wounds.
Contraindications
Hypersensitivity to the drug, pregnancy, lactation, childhood up to 12 years.
Special instructions
It is believed that St. John’s wort in high concentrations can damage reproductive cells.
Composition of
hypericum hypericum.
Dosage and administration
About 10 g (1.5 tablespoons) of St. John’s wort are placed in an enamel bowl, pour 200 ml (1 cup) of hot boiled water, close the lid, heat in a boiling water bath with periodic stirring for 15 minutes , cooled at room temperature for 45 minutes, filtered, the remaining raw materials are squeezed.
The volume of the resulting infusion was adjusted with boiled water to 200 ml.
Take orally in the form of heat 1/2 cup 3 times a day 30 minutes before meals. The course of treatment is 2-3 weeks. For rinsing, use 1/2 cup of warm infusion 3-4 times a day. The course of treatment is 5-10 days. Before use, it is recommended to shake the infusion.
Side effects
Allergic reactions: itching of the skin, skin rash, eczema, skin pigmentation, photosensitivity (most often in HIV-infected patients), increases sensitization to animal hair.
From the side of the central nervous system: anxiety, excessive fatigue, headache.
From the digestive system: nausea, epigastric pain, dry mouth, abdominal pain, flatulence, diarrhea or constipation, anorexia.
From the reproductive system: has a mutagenic effect on sperm and the egg.
Hematopoietic organs: iron deficiency anemia.
Drug interaction
When used with MAO inhibitors, it is possible to enhance effects and develop a hypertensive crisis.
With the simultaneous use of St. John’s wort can significantly affect the concentration in the blood plasma of any drugs metabolized with the participation of enzymes of the cytochrome P450 system.
With simultaneous use with digoxin, a decrease in the effectiveness of digoxin is possible, and after stopping the use of St. John’s wort preparations, an increase in the toxicity of digoxin is possible.
With the simultaneous use of tannic acids, which are present in St. John’s wort, can inhibit the absorption of iron.
There is a report of the development of acyclic bleeding with the simultaneous use of St. John’s wort with oral contraceptives containing a combination of ethinyl estradiol and levonorgestrel.
With the simultaneous use of St. John’s wort reduces the concentration of theophylline in plasma in patients regularly receiving theophylline.
With the simultaneous use of fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram, it is possible to enhance the effects and the development of serotonin syndrome (increased sweating, tremor, redness, confusion, agitation).
With simultaneous use with cyclosporine, a decrease in the concentration of cyclosporine in blood plasma is possible.
Storage conditions
In a dry, dark place cooked infusion – in a cool place for no more than 2 days.
Keep out of the reach of children!
The Expiration of
is 3 years. Do not use after the expiry date stated on the packaging.
Deystvuyuschee substances
Zveroboya prod ryavlennoho grass
Form of Treatment
s rye rastitelynoe
Krasnogorskleksredstva, Russia
