Description
Product form
tablets, film-coated
Packing
20 pcs.
Pharmacological action
Antiallergic, H1-histamine receptor blocker.
Indications
Seasonal and perennial allergic rhinitis and conjunctivitis (pruritus, sneezing, rhinorrhea, lacrimation, conjunctival hyperemia), urticaria (including chronic idiopathic urticaria), hay fever, fever () allergic dermatoses.
Contraindications
Hypersensitivity to cetirizine, other components of the drug, hydroxyzine, decreased renal function (creatinine clearance 30-49 ml / min), chronic renal failure, children under 6 years of age, pregnancy, lactation.
Precautions
Old age (possibly reduced glomerular filtration).
Use during pregnancy and lactation
The use of the drug during pregnancy is not recommended.
Since cetirizine passes into breast milk, it is not prescribed during the period of breastfeeding.
Special instructions
The simultaneous use of alcohol and drugs that inhibit the central nervous system is not recommended.
Influence on driving vehicles and mechanisms
During the treatment period, it is necessary to refrain from engaging in potentially dangerous activities that require an increased concentration of attention and speed of psychomotor reactions. Above a dose of 10 mg / day, the ability to react quickly may deteriorate.
Composition of
One tablet contains:
Active ingredient:
cetirizine dihydrochloride 0.01 g
Excipients:
microcrystalline cellulose – 0.034 g,
lactose monohydrate – 0.07 g, 0.07 pg, 0 kp
magnesium stearate – 0.0012 g,
silicon dioxide colloidal dioxide (aerosil) – 0.0012 g
Shell:
[hypromellose, talc, titanium dioxide, macrogol 4000 (polyethylene glycol 4000)] or [dry white film coat containing hypromellose , talc, titanium dioxide, macrogol 4000] – 0.004 g.
Dosage and administration
Inside, regardless of food intake, without chewing and drinking with a sufficient amount of liquid, preferably in the evening.
Adults and children over 6 years of age (weighing more than 30 kg) – 1 tablet once a day.
Side effects
The drug is usually well tolerated. Side effects occur rarely and are transient in nature.
From the digestive system: dry mouth, dyspepsia.
From the nervous system: dizziness, headache, drowsiness, fatigue, agitation, migraine.
Allergic reactions: angioedema, skin rashes, itching, urticaria.
Drug interaction
Joint use with theophylline (400 mg / day) leads to a decrease in the total clearance of cetirizine (theophylline kinetics does not change).
Myelotoxic drugs enhance the hematoxicity of the drug.
No clinically significant interactions with other drugs (pseudoephedrine, cimetidine, ketoconazole, erythromycin, azithromycin, diazepam, glipizide) were found.
overdose
Symptoms (single dose of 50 mg): dry mouth, drowsiness, delayed urination, constipation, anxiety, irritability.
Treatment: gastric lavage, symptomatic therapy. No specific antidote was detected. Hemodialysis is ineffective.
Storage Conditions
In a dark place at 2-25 ° C.
Shelf life
2 years.
Deystvuyushtee substance
Cetirizine
Terms and conditions
without prescription
dosage form
tablets
Vertex, Russia
