Description
Release form
Solution for external use.
Packaging
In a package of 3 bottles of 60 ml.
Pharmacological action
Drug for the treatment of baldness. It has a stimulating effect on hair growth in men and women with androgenetic alopecia (male pattern baldness).
The appearance of signs of hair growth is noted after 4 months or more of the use of the drug 2 times / day. The onset and severity of the effect may vary in different patients. After discontinuation of the drug, the growth of new hair stops, and after 3-4 months, the initial appearance can be restored.
The active substance of the drug – minoxidil – with systemic use has a vasodilating effect.
In controlled clinical trials after external use of the drug Regein in patients with both normal and high blood pressure, there were no systemic side effects associated with systemic absorption of minoxidil.
Indications
– androgenetic alopecia in men and women (in order to restore hairline or stabilize the process of hair loss).
Contraindications
– children and adolescents under 18
– hypersensitivity to minoxidil and other components of the drug.
The drug should not be applied with redness, inflammation, infection, soreness of the scalp (including with sunburn).
Use during pregnancy and lactation
Regein should not be used during pregnancy and lactation.
Special instructions
In addition to the hereditary predisposition, hair loss can be caused by other reasons. Regein does not prevent hair loss caused by certain drugs, malnutrition (iron or vitamin A deficiency in the body), or hair loss due to styling in tight hairstyles .
The patient should be warned about the need to consult a doctor in cases where hair loss began suddenly, baldness is focal in nature and the patient has a pathology from the cardiovascular system.
When systemic side effects appear (chest pains, palpitations, dizziness, decreased blood pressure, sudden weight gain, swelling of the arms and / or legs), as well as redness and irritation at the rubbing site, the drug should be discontinued and appropriate therapy should be prescribed if necessary.
In case of contact with eyes, damaged skin or mucous membranes, immediately rinse the affected area with plenty of running cold water. Avoid inhalation of the drug when sprayed.
In some patients, after the use of the drug, a change in the color and structure of the hair was observed.
Avoid rinsing off the drug, hair can be wet no earlier than 4 hours after the application of Regein.
During the use of Regein, you can use hair care products (including hair spray). In this case, you should first apply the drug and let the treated area of ² ¹ ² ¹the skin dry completely, and then apply the care products.
According to current data, hair dyeing, perm or using conditioners do not reduce the effectiveness of Regein, provided that the drug is completely washed off the hair and scalp before performing these procedures.
Composition
1 ml of the solution contains 50 mg minoxidil.
Dosage and administration
The drug is intended for external use only on the skin of the scalp. Do not apply Regein on the skin of other parts of the body.
Regein is applied to the scalp at a dose of 1 ml 2 times / day. (in the morning and in the evening), starting from the center of the affected area and around the affected area using special applicators. The drug is used at this dose, regardless of the size of the affected areas of the skin. The total daily dose should not exceed 2 ml.
Different applicators are used depending on the length of the hair and the size of the bald area. The drug should be applied to thoroughly dried skin and hair.
In order for the dose of the drug to be 1 ml, press the applicator pump directed to the center of the affected area 6 times. After applying the drug, wash your hands thoroughly.
To maintain a stable effect, continuous use of the drug is recommended. One bottle of the drug is designed for use within 30 days.
Side effects
Dermatological reactions:
often – redness, itching, peeling of the scalp
in some cases – hypertrichosis (unwanted body hair growth, including facial hair growth in women).
The use of the drug can cause increased hair loss during the transition from the resting phase to the hair growth phase (this temporary phenomenon occurs 2-6 weeks after the start of therapy and gradually stops within 2 weeks).
From the cardiovascular system: in some cases – arterial hypotension.
The drug is well tolerated. In clinical trials in patients with normal or elevated blood pressure, topical application of Regein was not accompanied by systemic side effects.
Drug interaction
When applied to Regein’s skin and topical products containing tretinoin, anthralin / dithranol (which cause a change in the protective function of the skin), minoxidil absorption may increase.
overdose
An overdose is unlikely if the recommended route of administration and dosing regimen is followed.
When taken accidentally, it should be taken into account that 5 ml of 2% and 2 ml of 5% of Regine contain 100 mg of minoxidil – the maximum recommended dose for adults in the treatment of hypertension.
Symptoms: systemic side effects associated with vasodilating properties of minoxidil (decreased blood pressure, tachycardia, dizziness, weight gain, syncope) may occur.
Treatment: the patient should be warned that in these cases it is necessary to urgently consult a doctor.
Storage Conditions
The product should be stored at room temperature (20 ° to 25 ° C).
active substance
Minoxidil
Without a prescription
lekarstvennaja form
spray for outdoor use
Aerosol-Service AG, Italy
