Description
Release form
Solution for intravenous and / m
Packing
20 ampoules of 5 ml each
Indications
as part of the complex treatment of acute myocardial infarction (from the first day)
as part of the complex therapy of ischemic stroke
discirculatory encephalopathy (including atherosclerotic origin)
mild and moderate cognitive impairment.
Contraindications
acute liver dysfunction
acute renal dysfunction
children and adolescents under 18 years of age (efficacy and safety not established)
pregnancy
lactation (breastfeeding)
hypersensitivity to the components of the drug.
Use during pregnancy and lactation
The use of the drug during pregnancy and during lactation is contraindicated.
Special instructions
For acute myocardial infarction, acute (ischemic stroke) and chronic (discirculatory encephalopathy) cerebrovascular accidents after completion of the parenteral administration of the drug, in order to maintain the achieved therapeutic effect, it is recommended to continue using Mexicor ® in capsule dosage form (100 mg capsule) 3 times / day). The duration of therapy is determined by the doctor.
Dosage and administration of
In the treatment of acute myocardial infarction, Mexico ® is administered intravenously or intravenously for 14 days with traditional therapy including nitrates, beta-blockers, ACE inhibitors, thrombolytics, anticoagulants and antiplatelet agents, as well as symptomatic indications.
In the first 5 days, to achieve the maximum effect, it is desirable to administer the drug in / in the next 9 days – the drug can be administered in / m.
In / in the introduction of the drug is carried out by drip infusion, slowly (to avoid side effects), in saline or 5% solution of dextrose (glucose) in a volume of 100-150 ml for 30-90 minutes If necessary, slow jet injection of a drug lasting at least 5 minutes is possible.
Administration of the drug (in / in or in / m) is carried out 3 times / day, every 8 hours. The daily therapeutic dose is 6-9 mg / kg body weight, a single dose is 2-3 mg / kg body weight. The maximum daily dose should not exceed 800 mg, a single – 250 mg.
In case of acute cerebrovascular accident (ischemic stroke), Mexicor ® is used as a part of complex therapy in the first 2-4 days iv in a drop of 200-300 mg 2-3 times / day, then in / m 100 mg 3 times / day . The duration of treatment is 10-14 days. Subsequently, the drug is administered orally in the form of capsules of 100 mg 2 times / day for 14 days and 100 mg 3 times / day for the next 7 days. The frequency and duration of repeated courses of therapy is determined by the doctor.
In case of dyscirculatory encephalopathy in the decompensation phase, Mexicor ® should be used intravenously in a drop or drop dose of 100 mg 2-3 times / day for 14 days. Then the drug is administered in / m at 100 mg / day for the next 2 weeks. In the future, the drug is prescribed in the form of capsules of 100 mg 2-4 times / day, the frequency and duration of the course of therapy is determined by the doctor.
For the course of prophylaxis of dyscirculatory encephalopathy, Mexicor ® is administered IM in a dose of 100 mg 2 times / day for 10-14 days.
For the treatment of mild and moderate cognitive impairment, Mexico ® is prescribed IM at a dose of 100-300 mg / day for 14 days. If necessary, in the future, the drug is used in capsule form, 100 mg 2-4 times / day (as recommended by a doctor) without limiting the course of treatment for the duration.
Side effects of
When given in the on / in, especially the jet, it is possible:
From the digestive system: dry and metallic taste in the mouth.
From the respiratory system: sore throat, discomfort in the chest and lack of air.
Other: a sensation of heat spreading throughout the body.
As a rule, these phenomena are due to the high speed of drug administration and are transient in nature.
Against the background of prolonged administration of the drug, the following side effects may occur:
From the digestive system: nausea, flatulence.
From the side of the central nervous system: sleep disturbances (drowsiness or falling asleep).
Drug Interactions
Mexico ® potentiates the effect of nitrates.
overdose
Symptoms: sleep disturbance (insomnia), in some cases drowsiness with / in the introduction in rare cases slight and short-term (up to 1.5-2 h) increase in blood pressure.
Treatment: the development of symptoms of overdose, as a rule, does not require the use of relief agents, these symptoms of sleep disorders disappear on their own within a day. In particularly severe cases, it is recommended to use one of the sleeping pills and anxiolytic medicines for ingestion (nitrazepam 10 mg, oxazepam 10 mg or diazepam 5 mg). With excessive increase in blood pressure, antihypertensive agents are used.
Storage Conditions
In a dark place at a temperature not exceeding 25 ° C.
Keep out of the reach and sight of children.
Shelf life
3 years
Active ee substance
tilmetilgidroksipiridina succinate
Pharmacy terms
Prescription
dosage form
injection and infusion
Appointment
Appointment
Adults prescribed by a doctor
EcoFarmInvest, Russia
