Description
Release form
Tablets
Packing
30 pcs.
Pharmacological action
Nootropic agent that dilates the vessels of the brain. It also has a tranquilizing, psychostimulating, antiplatelet and antioxidant effect. It improves the functional state of the brain due to the normalization of tissue metabolism and the effect on cerebral circulation (increases the volumetric and linear velocity of cerebral blood flow, reduces the resistance of cerebral vessels, inhibits platelet aggregation, improves microcirculation).
During a course admission, it increases physical and mental performance, reduces headache, improves memory, normalizes sleep, helps reduce or disappear feelings of anxiety, tension, and fear, improves the condition of patients with motor and speech disorders.
Indications
Cerebrovascular insufficiency, asthenia, depressive disorders in the elderly.
Conditions accompanied by anxiety, fear, increased irritability, emotional lability. Asthenic conditions caused by various neuropsychic diseases.
As part of a comprehensive treatment – to relieve acute alcohol intoxication in chronic alcoholism – to reduce asthenic, asthenoneurotic, postpsychotic, pre-relapse conditions, as well as alcoholic encephalopathy.
As part of complex therapy – migraine (prophylaxis), head injury, neuroinfection.
Improving the tolerance of physical and mental stress (to persons in tense and extreme conditions of activity to restore the physical performance of athletes, to increase resistance to physical and mental stress).
Open-angle glaucoma (to stabilize visual function).
In urological practice (in children over 3 years old and in adults with urinary disorders) to improve the adaptive function of the bladder (decrease in detrusor hypoxia).
Contraindications
Chronic renal failure, pregnancy, lactation, hypersensitivity to nicotinoyl gamma-aminobutyric acid.
Composition
Active ingredient: Picamilon – 20.00 mg N-nicotinoyl-gamma-aminobutyric acid sodium salt
Excipients: potato starch – 18.70 mg, corn starch – 0.60 mg, magnesium hydroxycarbonate (basic magnesium carbonate) – 15.53 mg, sucrose – 42.55 mg, calcium stearate – 1.00 mg, talc – 1.62 mg.
Dosage and administration
Take orally, regardless of food intake.
For cerebrovascular diseases, a single dose is 20-50 mg 2-3 times / day, a daily dose is 60-150 mg. The course of treatment is 1-2 months. Repeated course – after 5-6 months.
Depressive conditions of late age: 40-200 mg / day for 2-3 doses, the optimal dose range is 60-120 mg / day for 1.5-3 months. As an antiasthenic and anxiolytic agent – 40-80 mg / day, if necessary – up to 200-300 mg / day, for 1-1.5 months.
With alcoholism in the period of withdrawal, a dose of 100-150 mg / day is prescribed, a short course of 6-7 days with more persistent disorders outside withdrawal symptoms – 40-60 mg / day for 4-5 weeks.
To restore working capacity and with increased loads – 60-80 mg / day for 1-1.5 months, for athletes in the same dose, for 2 weeks. training period.
Parenteral administration in / in drip or stream (slowly), in / m.
In case of chronic cerebrovascular accident – in / in or in / m, 100-200 mg, 1-2 times / day, daily dose – 20-40 mg. Depending on the condition of the patient, iv / drip is used in the morning, iv / in the evening, or iv for 10 days, then / m. The course of treatment is 15-30 days.
To stop acute uncomplicated intoxication with ethanol as part of complex therapy, a saturating dose of 5 mg / kg and a supporting dose of 1.56 mg / kg / h in a volume of 2.5 l of the infusion solution is administered for 4 hours in the morning and evening.
In asthenic conditions, depending on the severity of the disease, in addition to ingestion, they are given IM in a daily dose of 20-40 mg for 1 month.
Side effects
Nausea, headache, dizziness, irritability, agitation, anxiety, allergic reactions (rash, itching).
Drug Interactions
Reduces the duration of action of barbiturates. Enhances the effect of narcotic analgesics.
Overdose
Symptoms: increased severity of adverse reactions.
Treatment: symptomatic.
Storage conditions
In a dry, dark place at temperatures below 25 ° C.
The Expiration of
is 3 years.
Deystvuyuschee substances
Nykotynoyl gamma amynomaslyanaya acid
PMA
tablets
Pharmstandard-Ufavita, Russia
