Description
Release form
Tablets.
Packing
50 pcs.
Pharmacological action
Rauwolfia alkaloids have antihypertensive and antiarrhythmic effects. Sedative effect is less pronounced than that of reserpine, but the hypotensive effect is practically not inferior to reserpine, while in some cases they are better tolerated.
The antihypertensive effect of Raunatin develops more slowly than that of reserpine.
Contraindications
arterial hypotension
depression
coronary circulatory insufficiency
organic myocardial lesions
aortic malformations
peptic ulcer of the stomach and duodenum srdlerkrd senility III nephritis
Use during pregnancy and lactation
Contraindicated in pregnancy (III trimester), during lactation.
Special instructions
Possible simultaneous or sequential use with other antihypertensive drugs (ganglion blockers, hydrochlorothiazide, hydralazine).
Composition
Active ingredient: Rauwolfia alkaloids 2 mg.
Dosage and administration of
Raunatin is taken orally after a meal. On the 1st day, take 1 tablet (2 mg – in terms of the amount of alkaloids) at night on the 2nd day – 1 tablet 2 times a day, on the 3rd day – 3 tablets, gradually increasing the total dose to 4- 6 tablets per day.
After achieving a therapeutic effect (after 10-14 days), the dose is gradually reduced to 1-2 tablets per day.
Side effects
Possible swelling of the nasal mucosa, increased sweating, asthenia, cardialgia, bradycardia, depression, decreased libido.
Drug Interactions
With caution, it is prescribed together with quinidine, guanethidine, cardiac glycosides, beta-adrenergic agonists and negative-risk beta-adrenergic agonists (risk )
Overdose
Symptoms: sweating, general weakness and marked hypotension. In severe cases, after a short period of euphoria, drowsiness, depression, hypodynamia, phenomena of marked parkinsonism, loss of consciousness, coma develop.
Treatment: cancellation of the drug, gastric lavage, intake of activated carbon. Forced diuresis is shown. With a marked decrease in blood pressure, with the collapse of the patient to lay with his legs raised. If necessary, intravenous administration of reopolyglukin or mesaton is indicated with the addition of angiotensinamide or 2% solution of norepinephrine hydrotartrate. Adrenomimetic agents are prescribed with great caution because of the risk of pulmonary edema. A 10% solution of caffeine sodium benzoate is administered subcutaneously. The presence of sharp respiratory depression or its delay require suction of mucus from the respiratory tract, intubation and conducting artificial ventilation of the lungs, oxygen therapy.
There are no specific antidotes for poisoning with raunatin and other preparations of rauwolfia.
Storage Conditions
In a dark place at a temperature not exceeding 20 ° C.
Shelf life
3 years.
Deystvuyushtee substance
Rauvolyfii alkaloid
Terms and conditions
prescription
dosage form
tablets
Possible product names
RAUNATIN TAB P / O 2MG No. 50 (PACKAGING CELLULAR CIRCUIT)
RAUNATIN TAB. P.O. 2MG No. 50
Raunatin tablets 2 mg, 50 pcs.
Health pharmaceutical company, Ukraine
