Description
Pharmacological action
Medication with antiviral activity. The active substance is made from mantadine. The antiviral effect is achieved due to the ability of the active component to inhibit the specific reproduction of the virus at an early stage immediately after its penetration into the cell.
More: http://medside.ru/rimantadin
Indications
Prevention and early treatment of influenza A in adults and children older than 7 years.
Contraindications
acute liver disease,
acute and chronic kidney disease,
thyrotoxicosis,
hypersensitivity to rimantadine,
pregnancy and lactation,
children under 7 years old,
for lactase deficiency, lactose intolerance, lactose / isomaltose malabsorption syndrome (because lactose is part of the drug).
Special instructions
When using rimantadine, an exacerbation of chronic concomitant diseases is possible. In elderly patients with arterial hypertension, the risk of hemorrhagic stroke increases.
With a history of epilepsy and ongoing anticonvulsant therapy with rimantadine, the risk of developing an epileptic seizure increases. In such cases, rimantadine is used at a dose of 100 mg per day simultaneously with anticonvulsant therapy.
With influenza caused by virus B, rimantadine has an antitoxic effect. Prophylactic is effective in contact with patients with the spread of infection in closed groups and at high risk of the disease during an influenza epidemic. Perhaps the emergence of drug-resistant viruses.
During the treatment period, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions.
Composition of
per tablet
active ingredients: rimantadine hydrochloride – 50 mg
excipients: lactose (milk sugar) – 60 mg, potato starch – 37 mg, calcium stearate – 1.5 mg, talc – 1.5 mg.
Dosage and administration
Inside after a meal with water.
Treatment for influenza should begin within 24-48 hours after the onset of symptoms of the disease.
Adults are prescribed 100 mg 3 times a day on the first day on the second and third days, 100 mg 2 times a day on the fourth and fifth days, 100 mg once a day. On the first day of the disease, it is possible to use the drug once in a dose of 300 mg.
Children aged 7 to 10 years are prescribed 50 mg 2 times a day from 11 to 14 years old – 50 mg 3 times a day. Older than 14 years – doses for adults. Accepted within 5 days.
For the prevention of influenza, adults are prescribed 50 mg once a day for up to 30 days. Children over 7 years old – 50 mg 1 time per day for up to 15 days.
Side effects of
on the digestive side: dry mouth, nausea, vomiting, loss of appetite, epigastric pain,
flatulence from the central nervous system: headache, dizziness, insomnia, neurological reactions, impaired concentration, drowsiness, anxiety, increased irritability,
tiredness other: hyperbilirubinemia, allergic reactions (skin rash, itching, hives).
Overdose of
Symptoms: agitation, hallucinations, arrhythmia.
Treatment: gastric lavage, symptomatic therapy: measures to maintain vital functions. Rimantadine is partially excreted during hemodialysis.
active substance
Rimantadine
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Irbitskij HFZ, Russia
