Description
Pharmacological action of
Gastal reduces the high acidity level of gastric juice to normal levels and eliminates digestive upsets. The drug also inhibits the action of pepsin, bile enzymes (lecithin) and bile acids, promotes the rapid healing of stomach ulcers and protects the mucous membrane from aggressive factors (stimulates the secretion of mucus and alkaline sodium bicarbonate, epidermal growth factor, increases the concentration of phospholipids, etc.). The effect of the drug occurs immediately after administration and lasts another 2 hours. The drug is not absorbed inside, but is excreted in the feces.
Indications
According to the indications for Gastal, it is used for: gastritis with high acidity, stomach and small intestine ulcers, heartburn, erosion of the gastric mucosa, reflux esophagitis, diaphragmatic hernia, acute pancreatitis, with delayed dyspepsia. An indication for Gastal is also the prevention of peptic ulcer.
Contraindications
– severe renal failure
– Alzheimer’s disease
– hypophosphatemia
– lactose intolerance, lactase deficiency or glucose-galactose malabsorption
– children under 6 years of age
– hypersensitivity to aluminum salts, magnesium or other components of the drug.
Caution should be used in chronic renal failure, during pregnancy and during breastfeeding, in adults and children over 12 years of age with a body weight of less than 50 kg, in children aged 6 to 12 years, in elderly patients.
Use during pregnancy and lactation
Use of the drug during pregnancy and lactation (breastfeeding) is possible only under medical supervision in cases where the intended benefits to the mother outweigh the potential risk to the fetus.
Special instructions
In patients with low body weight and in children over the age of 6 years, Gastal ® should be used in lower doses and for less time.
In patients with impaired renal function, it is not recommended to use Gastal ® in doses exceeding the recommended ones and for a longer time.
Continuous use for more than 2 weeks is possible only with the appointment of a doctor.
Composition
White tablets, round, with a flat and smooth surface and beveled edges.
1 tablet contains:
aluminum hydroxide-magnesium carbonate gel -450 mg
Excipients: mannitol, sorbitol, lactose, corn starch, sodium cyclamate, sodium saccharin, talc, magnesium stearate, peppermint flavoring (pepermint).
Dosage and administration of
The drug is taken orally. The tablet should be gradually absorbed (do not swallow whole).
Adults are prescribed 1-2 tablets. 4-6 times / day, but not more than 8 tab. within 24 hours. The drug is recommended to be taken 1 hour after a meal and before bedtime.
The maximum duration of admission is 2 weeks.
With heartburn, the drug is prescribed in recommended doses, regardless of food intake.
For the purpose of prevention, Gastal ® is used before the alleged irritating effect on the gastrointestinal mucosa.
For children aged 6 to 12 years, half the dose for adults is prescribed.
Side effects of the
From the digestive system: rarely (at least 0.01%, but less than 0.1%) – nausea, constipation, diarrhea, a change in taste.
Other: in exceptional cases, allergic reactions.
Drug Interactions
The interval between taking Gastal and other drugs should be 1-2 hours.
Gastal ® enhances the effects of levodopa and nalidixic acid.
With simultaneous use, it reduces and slows down the absorption of tetracycline antibiotics, ciproflocacin and ofloxacin, salicylates, isoniazid, naproxen, iron preparations, cardiac glycosides, indomethacin, aminazine, phenytoin, histamine blockers N1 receptors, beta-adrenergic drugs, beta-adrenergic drugs, , barbiturates.
M-anticholinergic drugs, slowing down gastric emptying, strengthen and lengthen the effect of the drug.
Overdose
Symptoms of acute overdose are not described.
Symptoms: with prolonged use in high doses of drugs containing aluminum and magnesium, the development of hypophosphatemia, hypocalcemia, hypercalciuria is possible, osteomalacia, osteoporosis, hypermagnesemia, hyperaluminemia, encephalopathy, nephrocalcinosis and impaired renal function. Perhaps increased side effects from the digestive system (constipation, diarrhea). In patients with renal failure, thirst, a decrease in blood pressure, hyporeflexia are possible.
Treatment: symptomatic treatment.
Storage conditions
The drug should be stored in a dry, out of reach of children at a temperature of no higher than 25 ° C
Term hodnosty
3 years
Deystvuyuschee substances
Hydrotaltsyt, magnesium hydroxide
pharmacy leave terms without prescription
Form of Treatment
tablets dlya rassas vaniya
Teva Pharmaceutical Enterprises Co., Ltd. Israel
