Description
Latin name
UROFURAGIN
Release form
Yellow-orange tablets, round, flat cylindrical, with a notch on one side and a bevel on both sides.
Packing
30 pcs. – blisters (1) – packs of cardboard.
Indications
– treatment of infectious and inflammatory diseases of the urinary tract (cystitis, urethritis, pyelonephritis) caused by
microorganisms sensitive to furazidine – prevention of infectious complications after surgical interventions on the genitourinary system.
Use during pregnancy and lactation
The use of the drug during pregnancy and during lactation (breastfeeding) is contraindicated.
Ingredients
1 tab:
Bisacodyl 5.00 mg
Excipients:
Potato starch
Lactose
Gelatin
Talc (magnesium hydrosilicate)
srdlfd 1 mg srdldpfrd8 mg corn starch – 27.5 mg, sucrose – 13.75 mg.
Dosage and administration of
The drug is taken orally after a meal.
For treatment, apply 100-200 mg 2-3 times / day for 7-10 days. If necessary, after a 10-15-day break, treatment is repeated. The maximum daily dose is 600 mg.
For the prevention of infectious complications after surgery on the organs of the genitourinary system, 50 mg is used once 30 minutes before surgery.
Side effects of
From the hematopoietic system: agranulocytosis, thrombocytopenia, aplastic anemia, eosinophilia.
From the nervous system: dizziness, headache, drowsiness, weakness, peripheral neuropathy, the development of polyneuritis.
From the side of the organ of vision: visual impairment.
From the cardiovascular system: intracranial hypertension.
From the respiratory system: shortness of breath, chest pain, cough with and without sputum, interstitial pneumonitis, pulmonary fibrosis.
From the digestive system: nausea, vomiting, decreased appetite, anorexia, diarrhea, pancreatitis, impaired liver function, cholestatic jaundice, hepatitis.
From the musculoskeletal system: myalgia, arthralgia.
From the skin and subcutaneous tissues: skin rash (including papular) enanthema, pruritus, exfoliative dermatitis, reversible alopecia.
Allergic reactions: angioedema, urticaria, erythema multiforme.
Other: fever.
Drug Interaction
When used with ristomycin, chloramphenicol, sulfonamides, the risk of haematotoxic effects is increased.
Concomitant use of other nitrofuran derivatives, as well as urine acidifying drugs (including ascorbic acid, calcium chloride) should be avoided.
Urine-blocking drugs accelerate the excretion of furazidine in the urine.
Ethanol can increase the severity of side effects.
Probenecid and sulfinpyrazone reduce urinary excretion of furazidine. This can lead to the accumulation of furazidine and its toxicity.
When co-administered with magnesium antacids, the absorption of furazidine is reduced.
Overdose
Symptoms: neurotoxic reactions, polyneuritis, impaired liver function, acute toxic hepatitis.
Treatment: drug withdrawal, high fluid intake, symptomatic therapy, antihistamines, vitamins of group B. There is no specific antidote.
Storage conditions
The drug should be stored out of the reach of children at a temperature not exceeding 25 ° C.
Expiration
3 years. Do not use after the expiry date.
Deystvuyuschee substances
Furazydyn
