Description
Release form
tablets
Pharmacological action of
Heptor belongs to the group of hepatoprotectors, has antidepressant activity, detoxifying, regenerating, antioxidant, antifibrotic and neuroprotective effects.
Ademethionine is involved in the biochemical processes of the body, while stimulating the production of endogenous ademetionine.
Ademethionine (S-adenosyl-L-methionine) is a biological substance found in all tissues and body fluids.
Its molecule is included in most biological reactions and as a methyl group donor, methylation of phospholipids in the lipid layer of the cell membrane (transmethylation), and as a precursor of physiological thiol compounds – cysteine, taurine, glutathione, one of the most important intracellular antitoxic agents, CoA, etc. . (trans sulfation), and as a precursor of polyamines – putrescine, stimulating cell regeneration and proliferation of hepatocytes, spermidine, spermine, which are part of the structure of ribosomes (a inopropilirovanie).
Indications
intrahepatic cholestasis
hepatitis of various origins: toxic (including alcoholic), viral, medicinal (antibiotics, antitumor, antituberculosis and antiviral drugs, tricyclic antidepressants, oral contraceptive contraceptives)
depressive syndromes, including secondary
alcohol withdrawal syndrome.
Contraindications
Children’s age.
Hypersensitivity to the drug.
Use during pregnancy and lactation
It is not recommended to prescribe the drug Heptor in the I and II trimesters of pregnancy and during lactation (breastfeeding).
Special instructions
Given the tonic effect of heptor, the drug is not recommended before bedtime.
Use in cases of impaired liver function
When prescribing heptor for patients with cirrhosis of the liver amid hyperazotemia, systematic monitoring of blood nitrogen levels is necessary.
Composition
Active substances:
ademethionine (in the form of S-adenosylmethionine) 400 mg.
Excipients:
crospovidone (polyplasdone X El-10),
microcrystalline cellulose,
mannitol,
magnesium stearate.
Shell composition:
acrylization,
hydroxypropylmethyl cellulose,
copovidone (ESD-630 plasdon),
polyethylene glycol 6000.
Dosage and Administration
Tablets should be swallowed whole without chewing. To improve the therapeutic effect, tablets are recommended to be taken between meals.
With maintenance therapy
The drug is administered orally in a daily dose of 800-1600 mg (2-4 tablets). The duration of maintenance therapy can be an average of 2-4 weeks.
Side effects
allergic reactions.
Storage conditions
Store in a dry, dark place at a temperature not exceeding 25 ° C.
Term hodnosty
4 years
Form of Treatment
tablets
