Description
Release form
Cream for external use.
Pharmacological action
GCS for external use from mild to moderate activity.
It has anti-inflammatory, antipruritic and vasoconstrictive effects.
The mechanism of anti-inflammatory action is completely unclear.
Alclomethasone is believed to induce the synthesis of phospholipase A2 inhibitors (lipocortins).
As a result, the release of arachidonic acid from membrane phospholipids is reduced.
This leads to inhibition of the synthesis of prostaglandins and leukotrienes (inflammatory mediators) from arachidonic acid.
Indications
Dermatoses and inflammatory skin diseases that respond to topical treatment with corticosteroids, including:
Eczema.
Atopic dermatitis, allergic and contact dermatitis (including phytodermatitis, photodermatitis and sunburn).
Psoriasis.
Allergic reactions to insect bites.
Afloderm ® cream is used for the treatment of acute and subacute stages of inflammatory skin diseases, including accompanied by exudation. Afloderm ® cream is recommended for the treatment of inflammatory skin diseases on delicate and sensitive parts of the body (face, neck, chest, genital area) and, if necessary, for additional hydration of the affected skin, which is carried out due to the components of the preparation base.
Contraindications
Hypersensitivity to alklomethasone or any of the auxiliary components of the drug.
Tuberculosis of the skin.
Cutaneous manifestations of syphilis.
Chicken pox.
Viral skin infections.
Dermal post-vaccination reactions.
Open wounds, trophic ulcers. children’s age (up to 6 months).
Use during pregnancy and lactation
Use of the drug Afloderm ® cream and ointment in pregnant women is allowed.
In these cases, the use should be carried out under the supervision of a doctor, be short-lived and be limited to small areas of the skin.
There are no data on teratogenic effects.
Afloderm ® cream and ointment may be used in nursing mothers.
Precautions must be observed when using the drug in nursing mothers, in particular, the drug should not be applied to the skin of the mammary gland before feeding.
Special instructions
Avoid contact with the eyes (due to the possible development of glaucoma and cataracts), as well as on open wound surfaces.
If the course of the disease is complicated by the development of a secondary bacterial or fungal infection, an antibacterial or antifungal agent must be added to the Afloderm ® therapy.
Influence on the ability to drive a car or perform work, requiring increased speed of physical and mental reactions
Data on the effect of the drug Afloderm ® on the ability to drive vehicles and mechanisms are not available.
Composition of
1 g of cream contains:
Active ingredient:
of alklomethasone dipropionate – 0.5 mg.
Excipients:
propylene glycol – 250 mg
chlorocresol – 1 mg
sodium dihydrogen phosphate dihydrate – 2.995 mg
phosphoric acid – 0.04 mg
cetostearyl alcohol (cetyl alcohol – 40% alcohol, 60% – 40% st cetostearate – 22.5 mg
macrogol glyceryl stearate – 30 mg
paraffin soft white – 210 mg
sodium hydroxide – qs
purified water – 410.96 mg.
Dosage and Administration
Externally. Afloderm ® cream is evenly applied with a thin layer on the affected skin 2-3 times a day. In children and in the period of aftercare, it is possible to use the drug 1 time per day. To prevent relapse in the treatment of chronic diseases, therapy should be continued for some time after the disappearance of all symptoms.
Afloderm ® can be used in children from the 6th month of life.
must be considered that in young children, skin folds and synthetic diapers can have an effect similar to the effect of an occlusive dressing, and increase the resorption of the active substance of the drug. In addition, a greater degree of systemic resorption is possible in children due to the relationship between the surface of the skin and body weight, as well as due to insufficient skin maturity.
It is not recommended to apply under occlusive dressings, in places where diapers and diapers come in contact with the skin. The maximum duration of treatment in children is 3 weeks. Longer use of the drug should be carried out only under the supervision of a doctor.
If there is no effect within 2 weeks, the diagnosis should be clarified.
With the passage of the acute period of the disease, the need to use the drug on the most dense areas of the skin (palms, feet), especially with increased dryness of the skin, as well as if it is necessary to manifest the anti-inflammatory effect of the drug in deeper layers of the skin, it is advisable to switch to the use of Afloderm ® in the form of an ointment.
With common dermatoses, along with the use of Afloderm ® ointment, for the treatment of dermatoses localized in delicate and sensitive areas of the skin (face, neck, chest, genital area), it is advisable to switch to the use of Afloderm ® in the form of a cream.
In addition, Afloderm ® cream has cosmetic advantages – it is easily absorbed and does not leave a greasy shine.
Side effects
Typically, the drug is well tolerated. Side effects with the external use of alklomethasone are rare and are reversible.
From the skin: with a frequency of 1% (for ointment) and 2% (for cream) – itching, burning, erythema with a frequency of 2% (for cream) additionally – dry skin, irritation, papular rash common to both dosage forms: infrequently – folliculitis, acneform rash, hypopigmentation, perioral dermatitis, dermatitis, secondary infection, skin atrophy, striae, prickly heat.
In case of hypersensitivity reactions or side effects, therapy should be discontinued and consult a doctor.
Drug Interactions
Unknown.
overdose
Symptoms: development of systemic side effects of ACS.
Treatment: symptomatic.
Storage conditions
At a temperature not exceeding 30 ° C.
Keep out of the reach and sight of children.
Shelf life
2 years.
Deystvuyushtee substance
alclometasone
Terms and conditions
without prescription
dosage form
cream
Prescribing
Prescribing
Prescribing
Pregnant as prescribed by a doctor, Children over 6 months of age, As prescribed by a doctor For nursing mothers as prescribed by the doctor
