Description
Packaging
Container 625 ml.
Pharmacological action
Nutriflex 70/180 lipid supplies the body with a protein synthesis substrate and energy through glucose during parenteral nutrition.
Amino acids enter the intravascular and intracellular depots of endogenous free amino acids to maintain homeostasis.
Dextrose is involved in various metabolic processes in the body, enhances redox processes in the body, improves the antitoxic function of the liver.
Entering the tissue, phosphorylates, turning into glucose-6-phosphate, which is involved in many parts of the body’s metabolism.
Contraindications
Disorders of amino acid metabolism
Disorders of fat metabolism
Hyperkalemia, hypernatremia
Severe metabolic disturbances (ketoacidosis, coma of unclear etiology)
Severe hyperglycemia, uncorrectable by doses of insulin up to 6 units / hour
Acidosis
Intrahepatic cholestasis
Severe hepatic and renal failure
Severe heart failure
Hemorrhagic diathesis srdlkrom fatty fibromyloid sardolcoma to any of
excipients General contraindications for parenteral nutrition:
Severe circulatory disorders (collapse and shock)
Severe gi tissue poxia
Hyperhydration conditions
Disruption of water-electrolyte balance
Acute pulmonary edema, decompensated heart failure
Composition
Isoleucine,
leucine,
lysine hydrochloride,
methionine,
phenylalanine,
threonine,
tryptophan,
valine,
arginine monoglutamate,
histidine hydrochloride monohydrate,
alanine,
aspartic acid,
glutamic acid,
glycine,
proline,
sodium acetate, srdlkrt sodium srldbrd, srd trihydrate,
sodium dihydrogen phosphate dihydrate,
potassium acetate,
sodium hydroxide,
glucose monohydrate,
sodium chloride,
calcium chloride dihydrate,
zinc acetate, sodium chloride, calcium phosphate, calcium magnesium,
, calcium magnesium,
acetate.
Dosage and administration
Intended for intravenous administration in peripheral and central veins.
The temperature of the emulsion to be introduced should be at room temperature.
The configuration of Nutriflex lipid chambers allows adding fat emulsion last, to pre-evaluate compatibility with other added drugs.
Method of mixing the contents of the chambers of the
container If you need to add other drugs to the Nutriflex lipid preparation, use the following method:
Remove the secondary plastic bag from the container, unfold and lay the container on a firm, level surface (on the table)
Pressing the upper left chamber of the container with both hands (containing a solution of glucose with electrolytes), destroy the septum separating it from the lower chamber (containing a solution of amino acids with electrolytes)
If necessary, add electrolytes, trace elements and other compatible medications (including water-soluble vitamins) through an additional port with a red protective cap
With two hands pressing on the upper right chamber of the container (containing fat emulsion), destroy the septum separating it from the lower chamber
Add fat-soluble vitamins if necessary optional port with red
protective cap Gently mix the contents of all container chambers.
If there is no need to add other drugs to Nutriflex lipid, use the following procedure:
Remove the secondary plastic bag from the container, unfold and place the container on a firm, level surface (on the table)
Pressing the two upper chambers of the container with two hands, destroy the partitions, separating them from the bottom
camera Gently mix the contents of all the cameras in the container.
To carry out the infusion after mixing the contents of the container chambers:
After moving the emulsion to the lower chamber, fold the container along the midline separating the empty upper chambers from the lower
Hang the container on the infusion stand by the special ring in the center of the
container Remove the white protective cap from the infusion port, connect the system for intravenous infusion and start the infusion at the speed specified in these instructions for use.
Doses:
are selected according to individual needs.
Children over 14 years old and adults
The maximum daily dose is 40 ml / kg body weight, which corresponds to
1.28 g of amino acids / kg body weight / ki,
2.56 g of glucose / kg body weight / ki,
1.6 g fat / kg body weight / ki.
Children 2 to 14 years old
These recommendations are based on average needs. The dose should be individually adapted depending on the age, stage of development and severity of the disease. To calculate the dose, the degree of hydration of pediatric patients must be taken into account.
For children, it may be necessary to start nutritional therapy with half the estimated dose. The dose should be increased to the maximum stepwise in accordance with the individual metabolic capabilities of the body.
For children from 2 to 5 years old, the daily dose is 45 ml / kg body weight, which corresponds to
1.44 g amino acids / kg body weight / ki,
2.88 g glucose / kg body weight / ki,
1.8 g fat / kg body weight / ki.
For children from 5 to 14 years old, the daily dose is 30 ml / kg body weight, which corresponds to
0. 96 g amino acids / kg body weight / ki,
1.92 g glucose / kg body weight / ki,
1.20 g fat / kg body weight / ki.
Due to the age-related characteristics of children, Nutriflex lipid may not fully satisfy the energy requirement. In these cases, a glucose solution or a fat emulsion may be added to the parenteral nutrition program as necessary.
Speed ² ¹ ² ¹of administration
Long-term administration of Nutriflex lipid is recommended. A stepwise increase in the infusion rate during the first 30 minutes reduces the incidence of possible complications.
The maximum infusion rate is 2.5 ml / kg body weight / h, which corresponds to
0.08 g amino acids / kg body weight / h,
0.16 g glucose / kg body weight / h,
0.1 g fat / kg body weight / h.
For a patient weighing 70 kg, the maximum infusion rate will be 175 ml / h. In this case, the rate of introduction of amino acids will be 5.6 g / h, glucose – 11.2 g / h, fat – 7. g / h.
Elderly patients
Doses do not differ from those recommended for other adult patients. However, metabolism can vary significantly in old age, so careful monitoring of this group of patients is necessary.
Patients with renal and / or liver failure
Doses are selected individually.
Duration of use of
Administration of the drug Nutriflex lipid is not recommended for more than seven days.
Storage conditions
In the dark place at a temperature of no higher than 25 ° C.
Shelf life
2 years
Active ingredient
Amino acids for parenteral nutrition, Other preparations Minerals
Pharmacy terms of delivery
Prescription
lekarstvennaja form
Ñmulsyya for infusions
