Description
Latin name
ANATOXINUM STAPHYLOCOCCUS
Release form
Purified staphylococcal toxin is a staphylococcal toxin neutralized with formalin and heat, purified from ballast proteins. The clear liquid is colorless or light yellow in color.
Packing
1 ml – ampoules (10) – packs of cardboard.
Pharmacological action
It has antitoxic, antimicrobial, immunomodulating and immunocorrective effects, it can cause the formation of antistaphylococcal immunity directed against both the microbe and the toxin.
Indications
Specific immunotherapy of acute and chronic (acute stage) staphylococcal infection in adults.
Contraindications
Contraindications for the use of purified staphylococcal toxoid are: acute infectious and non-infectious diseases of no staphylococcal etiology, chronic diseases of not staphylococcal etiology in the stage of exacerbation or decompensation – vaccinations are carried out no earlier than 1 month after recovery (remission).
Use with caution if there is a history of severe allergic reactions (anaphylactic shock, Quincke’s edema) during pregnancy (because there is insufficient data on the safety of the drug in pregnant women).
Use during pregnancy and lactation
There is insufficient data on the safety of the drug Anatoxin staphylococcal purified liquid in pregnant women.
Composition
1.0 ml of the drug contains from 10 to 14 EU (units of binding) staphylococcal toxoid.
The drug does not contain preservatives or antibiotics.
Dosage and administration
staphylococcal, purified toxoid is administered subcutaneously at the lower angle of the scapula, alternating the right and left sides with each subsequent injection. Intramuscular use of the drug is not allowed.
The drug is not suitable for use in ampoules containing impaired integrity, labeling, if physical properties (the presence of turbidity, flakes), expired, in violation of storage conditions are changed. Opening of ampoules and administration of the drug to patients is carried out with strict observance of the rules of asepsis and antiseptics.
The drug in an opened ampoule is not subject to storage.
The full course of treatment includes 7 injections of the drug, carried out with an interval of 2 days, in the following increasing doses: 0.1-0.3-0.5-0.7-0.9-1.2-1.5 ml.
With a quick clinical effect, the course of therapy at the discretion of the attending physician can be reduced to 5 injections.
Side effects
The introduction of the drug may be accompanied by general, local and focal reactions.
General reactions are characterized by mild weakness, malaise, and occasionally an increase in temperature to 37.5 ° C.
Local reactions are characterized by hyperemia and mild soreness at the injection site, disappearing after 1-2 days.
Often, after the injection of the drug, a focal reaction may occur, i.e. exacerbation of the process in the place of its localization.
The occurrence of these reactions is not a contraindication for continued treatment. However, if there are both general and local reactions, the interval between the previous and subsequent injections of the drug is recommended to be increased by 1 day. The development of a focal reaction does not require an increase in the interval between injections.
Drug Interaction
Treatment with staphylococcal purified anatoxin can be given at the same time as other general and local therapy, except for immunoglobulins and antistaphylococcal plasma.
Storage Conditions
According to SP 3.3.2. 1248-03 at a temperature of 2 to 8 ° C in a dry, dark place. Freezing is not allowed.
Transportation.
According to SP 3.3.2.1248-03 at 2 to 8 ° C. Freezing is not allowed.
Shelf life
2 years.
Deystvuyushtee substance
toxoid stafilokokkov y
Terms of drugstore
prescription
Le pd form
injection
Appointment Appointment
Adult prescribed by a doctor, For children prescribed by a doctor