Description
Latin name
Basiron AC
Release form
Gel for external use 5%
40 g
packaging
Pharmacological action of
Baziron AS has high antimicrobial activity against Propionibacterium acnes and Staphylococcus epidermidis, has comedonolytic and anti-inflammatory effects, improves tissue oxygenation, suppresses sebum production in the sebaceous glands, and absorbs excess skin.
Benzoyl peroxide, being a powerful oxidizing agent, has a strong bactericidal effect on microorganisms, while microorganisms are not able to produce strains resistant to benzoyl peroxide.
In an in vivo study, seeding showed that growth inhibition of Propionibacterium acnes by 94% was observed on day 7, and on day 15 by 97-99%.
The anti-inflammatory effect of benzoyl peroxide is based on the inactivation of free radicals in the focus of inflammation and inhibition of free fatty acids.
The basis of the preparation is represented by the acrylate copolymer / glycerin complex, which provides controlled adsorption of excess sebum and the gradual release of glycerin to soften and moisturize the skin.
Indications
Acne.
Contraindications
– children under 12 years of age
– hypersensitivity to the components of the drug.
Use during pregnancy and lactation
The use of Baziron AS is not recommended during pregnancy and during breastfeeding.
Composition
1 g of gel contains 50 mg benzoyl peroxide.
Excipients:
Acrylate copolymer
Poloxamer 182
Carbomer 940 (carbopol 980)
Glycerin
Disodium edetate
Sodium dioctyl sulphosuccinate
Propylene glycol
Sodium hydrochloride.
Dosage and administration
Gel should be applied to a clean and dry surface of affected skin 1 or 2 times / day (morning or evening). The course of treatment is 3 months.
The therapeutic effect develops 4 weeks after the start of the drug.
Persistent improvement occurs after 3 months of therapy.
Baziron AS is indicated for the treatment of mild to moderate acne with a predominance of pustular elements as monotherapy, and for moderate acne also in combination with other local (retinoids) and systemic (antibiotics, antiandrogens for oral administration).
If necessary, a second course of treatment is possible.
Drug interaction
There is currently no data on the drug interaction of the drug Baziron AS, which is used according to indications and recommended doses, with other drugs for external and systemic use.
Overdose
Symptoms: Severe irritation at the site of application may occur if a large amount of the preparation is accidentally applied to the skin.
Treatment: The drug should be discontinued and symptomatic therapy should be given.
Storage Conditions
The product should be stored at a temperature not exceeding 25 ° C.
Shelf life
3 years.
Deystvuyushtee substance
Benzoyl peroxide
Terms and conditions
without prescription
Dosage form
gel for external use
Prescribing
Prescribing
For adults, Children over 12 years old
Galderma Laboratories, France
