Description
Latin name
Halidor
Release form
White or grayish-white tablets, round, flat, chamfered, with HALIDOR engraving on one side, with a faint characteristic odor.
packaging 10 pcs
Indications
Vascular diseases: – peripheral vascular disease – Raynaud’s disease, other diseases with acrocyanosis and vascular spasm, as well as chronic obliterating artery diseases
– cerebrovascular disease: in the treatment of acute and chronic cerebral ischemia.
To eliminate spasm of internal organs: – gastrointestinal diseases – gastroenteritis of various etiologies (especially infectious), infectious and inflammatory colitis, functional diseases of the large intestine, tenesmus, postoperative flatulence, cholecystitis, gallstone disease, condition after cholecystectomy, dyskinesia with dyskinesia Oddie peptic ulcer of the stomach and duodenum (as part of combination therapy)
– urological syndromes: spasms and tenesmus of the bladder, concomitant therapy of urolithiasis (in combination with analgesics for renal colic)
Preparation for instrumental methods of research in urology (for solution for i / in and / m introduction).
Contraindications
– severe respiratory failure
– severe renal failure
– severe hepatic insufficiency
– acute myocardial infarction
– acute myocardial infarction and other acute – recent hemorrhagic stroke
– traumatic brain injury (within the last 12 months)
– pregnancy
– lactation (breastfeeding)
– children and adolescents under 18 years of age (lack of experience)
– hypersensitivity to the components of the drug Halidor.
Use during pregnancy and lactation
There were no adequate and strictly controlled clinical studies on the use of the drug Halidor ® during pregnancy and lactation. Therefore, the introduction of the drug to patients in the first trimester of pregnancy is not recommended.
If you need to use the drug during lactation, you should decide whether to stop breastfeeding during treatment.
Preclinical studies did not reveal any embryotoxic or teratogenic effects.
Composition
1 tab.: – bicyclan fumarate 100 mg
Excipients: potato starch, polyvinyl acetate, magnesium stearate, carbomer 934 P, sodium carboxymethyl starch (type A), silicon dioxide colloidal anhydrous, talc.
Dosage and administration of
Vascular diseases: Inside, Halidor ® is prescribed 100 mg 3 times / day. within 2-3 months. The maximum daily dose for oral administration is 400 mg. The interval between courses is 2-3 months.
The drug can also be used as IV infusions in a daily dose of 200 mg divided into 2 injections. Before the infusion, 100 mg (4 ml) of the drug is diluted in 100-200 ml of an isotonic sodium chloride solution and injected intravenously for 1 h 2 times / day.
To eliminate spasm of internal organs: Inside, Halidor ® is prescribed in a dose of 100-200 mg once, but not more than 400 mg / day. For maintenance therapy, 100 mg 3 times / day is prescribed. for 3-4 weeks, then 100 mg 2 times / day. The duration of treatment is determined individually depending on the disappearance of the symptoms of the disease and, as a rule, does not exceed 1-2 months.
In acute cases, Halidor ® is administered iv slowly at a dose of 100-200 mg (4-8 ml) or IM deeply at a dose of 50 mg (2 ml). Before iv administration, the required amount of solution is diluted with an isotonic sodium chloride solution to 10-20 ml. The course of treatment is 2-3 weeks with the subsequent transfer of the patient, if necessary, to take the drug Halidor ® inside.
Side effects of the
From the digestive system: dry mouth, abdominal pain, feeling full, nausea, vomiting, decreased appetite, diarrhea, increased activity of hepatic transaminases in serum.
From the side of the central nervous system: anxiety, dizziness, headache, impaired gait, tremor, sleep disturbances, insomnia, memory disorders rarely – transient confused state of consciousness, epileptiform seizures, hallucinations in elderly patients in rare cases – symptoms of focal CNS damage.
From the cardiovascular system: sometimes – atrial and ventricular tachyarrhythmias (especially when co-administered with other proarrhythmogenic drugs).
Other: general malaise, weight gain, leukopenia, allergic reactions rarely – thrombophlebitis with iv administration.
Drug Interaction
When used concurrently, Galidor ® exacerbates the CNS’s depressant effects on anesthetics and sedatives.
When used with sympathomimetics, the risk of tachycardia, atrial and ventricular tachyarrhythmias is increased.
With the simultaneous use of Galidor and potassium-lowering drugs (including diuretics, cardiac glycosides) and quinidine, summarization of proarrhythmogenic effects is possible.
When used with digitalis, the risk of arrhythmia in overdosage of cardiac glycosides is increased.
When using Galidor with beta blockers, it may be necessary to select a beta blocker dose because of the opposite of chronotropic effects (negative for beta blockers and positive for benzyclan).
When used with calcium channel blockers and other antihypertensive drugs, their effect may be enhanced.
When used with Galidor with antispasmodic drugs, summation of these effects is possible.
When used with acetylsalicylic acid, platelet aggregation inhibition may be increased.
Overdose
Symptoms: increase in heart rate, decrease in blood pressure, collapse, impaired renal function, incontinence, drowsiness, anxiety, in severe cases – epileptiform seizures. A significant overdose can cause tonic and clonic seizures. Allergic reactions.
Treatment: carrying out symptomatic therapy. When taking a large number of tablets, you should wash your stomach. It is recommended that benzodiazepines be used to treat seizures. The specific antidote is unknown. There are no data on the possible excretion of benzyclane by dialysis.
Storage conditions
The drug should be stored out of the reach of children at a temperature of 15 ° to 25 ° C.
Expiration
5 years.
Deystvuyuschee substances
Bentsyklan
dispensing terms
pharmacy sdflfp41 pf71 pdf17 pf17171 and a half for pdf71
Prescription
dosage form
dosage form
tablets
