Description
Packing
30 pcs
Pharmacological action
Betagistin – histaminergic, improves microcirculation.
Pharmacodynamics
Agonist of H1 receptors of vessels of the inner ear and antagonist of H3 receptors of the vestibular nuclei of the central nervous system Through direct agonistic action on the H1 receptors of the vessels of the inner ear, as well as indirectly through the action on the H3 receptors, it improves microcirculation and capillary permeability, normalizes endolymph pressure in the labyrinth and cochlea, and increases blood flow in the basilar artery.
It has a pronounced central effect, being an inhibitor of the H3 receptors of the vestibular nerve nuclei. It improves the conductivity in the neurons of the vestibular nuclei at the level of the brain stem.
The clinical manifestation of these properties is a decrease in the frequency and intensity of dizziness, decrease in tinnitus, improvement in hearing if it is reduced.
Pharmacokinetics
Absorbed rapidly, binding to plasma proteins is low. The time required to reach Cmax is 3 hours.
It is almost completely excreted by the kidneys as a metabolite (2-pyridylacetic acid) within 24 hours. T1 / 2 – 3-4 hours.
Indications
treatment and prevention of vestibular dizziness of various origins
syndromes, including dizziness and headache, tinnitus, progressive hearing loss, nausea and vomiting
disease or Meniere’s syndrome.
Use during pregnancy and lactation
Insufficient data to evaluate the effects of the drug during pregnancy and lactation. In this regard, it is not recommended to take during pregnancy. At the time of treatment, it is necessary to stop breastfeeding.
Composition
1 tablet contains:
Active ingredient: betahistine dihydrochloride 8 mg
Excipients: MCC lactose (milk sugar) citric acid silicon monohydrate colloidal dioxide (aerosil) crospovidone talc magnesium stearate.
Dosage and Administration
Inside, with food. 1 / 2-1 tablets 3 times a day.
Improvement is usually noted already at the beginning of therapy. A stable therapeutic effect occurs after two weeks of treatment and can increase over several months of treatment. The treatment is long. The duration of the drug is selected individually.
Side effects
Gastrointestinal disturbances, the appearance of hypersensitivity reactions from the skin (rash. itching. urticaria), Quincke’s edema.
Overdose
Symptoms: nausea, vomiting, cramps.
Treatment: gastric lavage, intake of activated carbon, symptomatic therapy.
Storage Conditions
In a dry, dark place at a temperature not exceeding 25 ° C. Keep out of reach of children.
Expiration
2 years.
active substance
Betahistine
Terms leave through pharmacies
In retseptu
The dosage form of
tablet
Prescription
For adults as prescribed by a doctor
Indications
Indications
cerebrovascular disease Meniere
Canonfarma, Russia p19frewfrooffonfonyf196419f1964 . Russia
