Description
Release form
tablets
Pharmacological action of
Betagistin acts primarily on histamine H1 and H3 receptors located in the vestibular nuclei of the central nervous system (CNS) and inner ear.
The drug improves the permeability of the capillaries of the inner ear and the microcirculation processes in them, and also normalizes the pressure of the endolymph in the cochlea and the labyrinth through a direct agonistic effect on the H1 receptors located in the vessels of the inner ear, as well as indirect effects on the H3 receptors.
At the same time, the active substance of the drug increases blood flow in the basilar artery. Betagistin is characterized by a pronounced central effect, being an inhibitor of H3 receptors, the localization sites of which are the nuclei of the vestibular nerve.
The drug improves the conductivity in the neurons of the vestibular nuclei at the level of the brain stem.
The above properties provide a therapeutic effect, which is expressed in the normalization of hearing in case of deterioration, a decrease in tinnitus, and a decrease in the intensity and frequency of dizziness.
Betahistin enhances the tone of the gastrointestinal tract (GIT) and smooth muscles of the bronchi, and can also enhance the secretion of gastric juice.
Indications
– Treatment and prevention of vestibular dizziness of various origins
– Syndromes including dizziness and headache, tinnitus, progressive hearing loss, nausea and vomiting
– Meniere’s disease / syndrome.
Contraindications
– Hypersensitivity to any of the components of the
preparation – pregnancy and lactation (due to insufficient data).
Precautions:
Peptic ulcer of the duodenum (including history), pheochromocytoma, bronchial asthma. These patients should be regularly observed during treatment.
Directions for use
Inside, with food.
Betaver 8 mg: 1-2 tablets 3 times a day.
Betaver 16 mg: 1 / 2-1 tablet 3 times a day.
Improvement is usually noted already at the beginning of therapy, a stable therapeutic effect occurs after two weeks of treatment and can increase over several months of treatment.
The duration of the drug is selected individually.
Composition of
Composition 1 tablet:
active ingredient:
betahistine dihydrochloride – 8 mg, 16 mg or 24 mg
auxiliary components:
povidone,
silicon dioxide colloid,
c sodium microcrystal sodium, sodium carbdryl sodium ,
corn starch.
Side effects
Gastrointestinal upset.
In very rare cases, the appearance of hypersensitivity reactions from the skin (rash, itching, urticaria), Quincke’s edema was reported.
Overdose
Symptoms: nausea, vomiting, seizures may occur when taking a dose of more than 640 mg.
Treatment: gastric lavage, intake of activated carbon, symptomatic therapy.
Storage conditions
At a temperature not exceeding 25 ° C.
Keep out of the reach of children.
Expiration
4 years.
Do not use after expiration date.
Deystvuyuschee substances
betahistine
Terms and conditions otpuska IZ
pharmacy prescription
Dosage form
tablets
appointment
Dlya vzrosl h in naznacheniyu Vracha
Indications
disease Meniere, Violation of cerebral circulation
