Description
Release form
Ointment for external use.
Pharmacological action
Rederm is a combined preparation for external use, the effect of which is due to its constituent components, the drug has anti-inflammatory, anti-allergic, antipruritic, keratolytic effects.
Betamethasone inhibits the release of inflammatory mediators, prevents the marginal accumulation of neutrophils, reduces inflammatory exudate and cytokine production, reduces macrophage migration, leading to a decrease in the processes of infiltration and granulation.
Thanks to the presence of salicylic acid, it softens the skin, eliminates horny deposits and promotes deeper penetration of betamethasone.
Indications
Rederm is indicated for use in the treatment of subacute and chronic dermatoses accompanied by hyperkeratosis and desquamation:
psoriasis, dyshidrotic dermatitis, eczema, neurodermatitis, lichen planus, ichthyosis and ichthyroid dermatitis and atopic dermatitis dermatitis dermatitis dermatitis
urticaria, erythema multiforme erythema
simple chronic lichen (limited neurodermatitis).
Dermatoses that cannot be treated with other glucocorticosteroids (especially lichen red warty), skin dyshidrosis.
Contraindications
Children under 2 years of age, lactation, hypersensitivity, open wounds, bacterial, viral and fungal skin diseases (pyoderma, syphilis, tuberculosis of the skin, chickenpox, herpes, actinomycosis, blastomycosis, sporotrichosis)
post-vaccination skin reactions, perioral dermatitis, rosacea venous, trophic venosis failure, skin tumors (skin cancer, nevus, atheroma, epithelium, melanoma, hemangioma, xanthoma, sarcoma).
Precautions:
Hepatic failure, childhood (over 2 years), prolonged therapy, especially with occlusive dressings.
Use during pregnancy and lactation
The safety of using local glucocorticosteroids in pregnant women has not been established.
Prescribing this group of drugs during pregnancy is justified only if the potential benefit to the mother outweighs the potential risk to the fetus.
During pregnancy, this group of drugs should not be used in high doses or for a long time.
It has not been established whether topical use of glucocorticosteroids can cause them to appear in mother’s milk, therefore, the question of stopping breastfeeding should be decided.
Special instructions
Avoid contact with the eyes, do not apply on the skin near the eyes and on the mucous membranes. The drug is not intended for use in ophthalmology. With prolonged treatment, when applying the drug to large surfaces of the skin, when using occlusive dressings, systemic absorption of glucocorticosteroids is possible.
Long-term use on the skin of the face is not recommended – it is possible to develop dermatitis such as rosacea, perioral dermatitis, skin atrophy and acne to avoid use in the anogenital area.
Rederm ointment is most suitable for the treatment of patients with dry and brittle skin.
If signs of hypersensitivity or skin irritation associated with the use of the drug are noted, treatment should be discontinued and adequate therapy should be selected for the patient.
With prolonged use of the drug, its withdrawal should be carried out gradually.
Pediatric use:
For children from 2 years of age, the drug is prescribed only according to strict indications and under medical supervision, since the development of systemic side effects associated with betamethasone is possible.
The duration of treatment should be as short as possible. When using the Rederm preparation on large surfaces and / or under an occlusive dressing, it is possible to suppress the function of the hypothalamic-pituitary-adrenal system and the development of symptoms of hypercorticism, a decrease in growth hormone excretion, an increase in intracranial pressure can be observed.
Composition of
100 g:
– betamethasone dipropionate in terms of betamethasone 0.05 g
– salicylic acid 3.0 g
excipients:
liquid paraffin (paraffin paraffin, vaseline white paraffin, white paraffin white soft).
Dosage and Administration
Externally. Apply to the affected areas at the rate of: a column of Roderm ointment with a length of 0.5 cm on a skin area of ​​approximately 7 cm? 7 cm, rubbing slightly, with a thin layer 2 times a day.
Another frequency of use may be determined by your doctor based on the severity of the disease. In mild cases, the ointment is sufficient to apply, as a rule, once a day for more severe lesions, more frequent use may be necessary.
If necessary, apply occlusive dressings, which change every 24 hours.
The duration of treatment depends on the effectiveness and tolerability of therapy and is 2-4 weeks.
If clinical improvement does not occur, the diagnosis must be clarified.
Side effects
– Burning, irritation, dryness, hypopigmentation, itching of the skin, folliculitis, hypertrichosis, dermatitis, acne-like rashes.
– When using occlusive dressings – maceration of the skin, striae, skin atrophy, secondary infection, prickly heat.
– With prolonged use – skin atrophy, local hirsutism, telangiectasia, purpura, hypopigmentation, hypertrichosis.
– When applied to large surfaces – systemic manifestations of side effects of glucocorticosteroids (growth retardation, Itsenko-Cushing’s syndrome, increased intracranial pressure after treatment, hyperglycemia, glucosuria, hypokalemia, increased blood pressure) or salicylates (pallor, increased fatigue, drowsiness, hyperventilation against the background of tachypnea, nausea, vomiting, hearing impairment, confusion).
Overdose
Acute overdose is unlikely, however, with excessive or prolonged use of the drug, a chronic overdose is possible, accompanied by signs of hypercorticism: hyperglycemia, glucosuria, reversible inhibition of adrenal cortex function, manifestation of Cushing’s syndrome.
treatment.
Appropriate symptomatic treatment is indicated. In case of chronic toxic effects, gradual discontinuation of the drug is recommended.
Deystvuyuschee substances
betamethasone, salicylic acid
Terms of dispatch from
pharmacies Without a prescription
Dosage form
ointment
Vertex, Russia
