Description
Release form
Solution for oral administration.
Packing
Bottle 60 ml.
Pharmacological action
Bromhexine 4 Berlin-Chemie has a mucolytic (secretolytic) and expectorant effect.
The mucolytic effect is associated with the depolymerization and liquefaction of mucoprotein and mucopolysaccharide fibers.
Indications
Acute and chronic bronchopulmonary diseases accompanied by the formation of sputum with increased viscosity:
Bronchial asthma.
Pneumonia.
Tracheobronchitis.
Obstructive bronchitis.
Bronchiectasis.
Emphysema of the lungs.
Cystic fibrosis.
Tuberculosis.
Pneumoconiosis.
Contraindications
Hypersensitivity to the components of the drug.
Peptic ulcer (in the acute stage).
Pregnancy (I trimester).
Lactation.
Precautions: renal and / or liver failure of bronchial disease, accompanied by an excessive accumulation of secretion, a history of gastric bleeding in children up to 2 years old.
Use during pregnancy and lactation
The use of the drug during pregnancy is possible only if the intended benefit to the mother outweighs the potential risk to the fetus.
The use of the drug during lactation is contraindicated.
Special instructions
During treatment, a sufficient amount of liquid must be taken, which increases the expectorant effect.
The elimination half-life of bromhexine increases with severe renal impairment. Therefore, patients with impaired renal function should be prescribed bromhexine in smaller doses or in normal doses, but at large intervals.
In cases of impaired bronchial motility or a significant amount of sputum excreted (for example, with rare malignant ciliary syndrome), the use of Bromhexin 4 Berlin-Chemie requires caution because of the risk of delayed discharge in the airways.
The use of Bromhexine 4 Berlin-Chemie in children under 2 years of age is possible only under the supervision of a physician.
Indication for patients with diabetes mellitus: 5 ml of solution (1 scoop) contains 2 g of sorbitol, which corresponds to 0.17 bread units.
Composition of
5 ml solution contains:
Active ingredient:
bromhexine hydrochloride – 4 mg.
Excipients:
propylene glycol – 25 g,
sorbitol – 40 g,
aromatic concentrate with an apricot odor – 0.05 g,
hydrochloric acid 0.1 M (3.5% solution) – 0.156 g,
purified water – 49.062 g
Dosage and administration of
The drug is taken orally.
Adults and adolescents over 14 years of age: 3 times / day for 2-4 measured spoons (daily dose – 24-48 mg of bromhexine).
Children from 6 to 14 years old, as well as patients weighing less than 50 kg: 3 times / day, 1-2 scoops (daily dose is 12-24 mg of bromhexine).
Children under 6 years: 3 times / day in 1 scoop (daily dose – 12 mg bromhexine).
During treatment, it is recommended that you use a sufficient amount of fluid to maintain the secretolytic effect of bromhexine. Without a doctor’s advice, you can not take bromhexine for more than 4-5 days.
Side effects
Possible: nausea, vomiting, dyspeptic symptoms, peptic ulcer exacerbation.
Rarely: allergic reactions develop (skin rash, rhinitis, swelling), shortness of breath, fever and chills, anaphylactic shock, dizziness and headaches, increased levels of transaminases in the blood serum.
In patients with sorbitol / fructose intolerance under the influence of sorbitol contained in the Bromhexin 4 Berlin-Chemie preparation, nausea, vomiting and diarrhea, a decrease in blood sugar (accompanied by trembling, cold sweat, palpitations, a sense of fear) may also be observed, increase activity of hepatic transaminases (extremely rare).
In case of side effects, the drug should be discontinued and consult a doctor.
Drug Interactions
Bromhexine 4 Berlin-Chemie can be prescribed simultaneously with other drugs used in the treatment of bronchopulmonary diseases.
Bromhexine 4 Berlin-Chemie is not prescribed simultaneously with antitussive drugs (including those containing codeine), as they can make it difficult to cough up sputum diluted with Bromhexine 4 Berlin-Chemie.
Bromhexine 4 Berlin-Chemi promotes the penetration of antibiotics (erythromycin, cephalexin, oxytetracycline, ampicillin, amoxicillin) into the lung tissue.
overdose
Symptoms: nausea, vomiting and other gastrointestinal disorders are possible.
Treatment: there is no specific antidote. If you overdose, you should induce vomiting and then give the patient fluid (milk or water). Gastric lavage is recommended within 1-2 hours after taking the drug.
Storage conditions
Keep out of the reach and sight of children at temperatures not exceeding 25 ° C.
Shelf life
3 years. Shelf life after the first opening of the bottle is 3 months.
Deystvuyushtee substance
Bromgeksin
Pharmacy terms
Without a prescription
Appointment
Appointment
Pregnant II and III trimester as prescribed by the doctor, Children over 2 years old, For adults
