Description
Description
Calcemin Advance 60
Complex of calcium, Vitamin D3 and minerals 1 vitamin D3 and 1
supplement minerals for the prevention of bone fragility and the complex treatment of osteoporosis.
With age, calcium is washed out of the bones and they become brittle.
Unlike other calcium preparations (3), Calcemin Advance contains special minerals (magnesium, zinc, manganese, copper, boron) to form a collagen network that holds calcium in bone tissue, preventing its leaching (4).
Calcemin Advance applies:
– for the prevention and comprehensive treatment of osteoporosis
– to improve the healing of
fractures – to compensate for the deficiency of calcium and trace elements
Calcemin Advance – so that the bones remain strong!
1. There are contraindications. Before use, consult a specialist.
2. compared with Calcemin
3. In the ATX group: A12AX (Calcium preparations in combination with other drugs)
4. Gromova OA, Torshin I.Yu. et al. Calcium and collagen biosynthesis: a systematic analysis of molecular mechanisms of exposure // Russian Medical Journal. 2016. No. 15. P. 10091017.
sponge release form
coated tablets
packaging 60 pcs
Pharmacological action
Combined preparation containing vitamins, micro and macro elements.
The action is determined by the properties that make up the ingredients.
Indications
Prevention and comprehensive treatment of osteoporosis of various origins:
– in women during menopause (natural and surgical)
– in people who take GCS and immunosuppressants for a long time.
Therapy of diseases of the musculoskeletal system (to improve the consolidation of traumatic fractures)
To supplement the deficiency of calcium and trace elements in adolescents.
Contraindications
Increased individual sensitivity to the components of the drug, vitamin D hypervitaminosis, hypercalcemia and hypercalciuria, severe renal failure, urolithiasis, nephrolthiasis, the active form of tuberculosis, sarcoidosis, childhood (up to 12 years), an allergic reaction to peanut butter and soy, as the composition of the drug includes soy polysaccharide.
Precautions:
Period of pregnancy and lactation, renal failure.
Use during pregnancy and lactation
During pregnancy and breastfeeding, the drug should be agreed with the doctor.
the adjusted dose should not exceed 1500 mg of calcium and 600 IU of vitamin D3, hypergalcemia that develops against the background of an overdose during pregnancy can cause mental and physical defects in the fetus.
In lactating women, it should be borne in mind that colecalciferol and its metabolites pass into breast milk, therefore, calcium and vitamin D3 intake must be considered.
Composition
Active ingredients:
calcium (calcium citrate and calcium carbonate) 500 mg,
colecalciferol (vitamin D3) 200 IU,
magnesium 40 mg, zinc 7.5 mg,
copper 1 mg,
manganese 1.8 mg
boron 250 mcg.
Excipients:
maltodextrin 25 mg,
microcrystalline cellulose 49.05 mg,
croscarmellose sodium 38 mg,
stearic acid 16, 3 mg,
soybean polysaccharide 15 mg, sodium lauric sulfide 5 mg.
Shell:
hypromellose 26, 328 mg,
titanium dioxide 12, 643 mg,
magnesium silicate 5 mg,
triacetin 5, 689 mg,
mineral oil 2, 845 mg,
dye red No. 40 (dye red charming) 0, 316,
dye yellow No. 6 (sunny sunset yellow) 0, 079 mg,
dye blue No. 1 0, 04 mg.
Description:
Oval biconvex tablets, coated with a pink shell with a notch on one side.
Dosage and administration of
Take orally with food.
Complex treatment of osteoporosis – 1 tablet 2 times a day.
Prevention of osteoporosis – 1 tablet per day.
When using the drug for the prevention and in the treatment of osteoporosis, the duration of treatment is determined individually by the doctor. The average duration of the course for prevention is 2 months, for the treatment of osteoporosis – 3 months.
Therapy of diseases of the musculoskeletal system: to improve the consolidation of traumatic fractures – 1 tablet per day, the duration of treatment is 4-6 weeks.
To supplement the deficiency of calcium and trace elements in adolescents from 12 years old – 1 tablet per day. The average duration of treatment is 4-6 weeks.
Side effects
Nausea, vomiting, flatulence, diarrhea, constipation, hypercalcemia, hypercalciuria, allergic reactions (itching, rash, urticaria).
Drug Interaction
When administered with Calcemin with Vitamin A, vitamin D3 toxicity is reduced. Phenytoin, barbiturates, ACS reduce the effectiveness of vitamin D3.
Laxatives reduce the absorption of vitamin D3. GCS, hormonal contraceptives for systemic use, levothyroxine worsen the absorption of calcium ions. At simultaneous use of tetracyclines the interval between receptions should be not less than 3 h, bisphosphonates and sodium fluoride (their absorption is broken) – not less than 2 h.
When combined with the preparation Calzemin with cardiac glycosides, their toxicity is increased (clinical control is needed) with thiazide diuretics – increases the risk of hypercalcemia, with furosemide and other loop diuretics – increases the excretion of calcium by the kidneys. Calcium should not be used concomitantly with calcium channel blockers.
Co-administration with antacids is not recommended, containing aluminum due to their reduced efficiency.
Overdose
Vitamin D hypervitaminosis, hypercalcemia and hypercalciuria.
Symptoms: decreased appetite, thirst, polyuria, dizziness, fainting, constipation, nausea and vomiting, muscle weakness, headache, coma, fatigue, bone pain, psychiatric disorders, nephrocalcinosis, abdominal pain, urinary pain, cases – cardiac arrhythmias.
With prolonged use in doses above 2500 mg calcium – kidney damage, soft tissue calcification.
In case of detection of the first signs of overdose, it is necessary to reduce the dose or stop the use of the drug, see a doctor.
In case of hypercalciuria exceeding 7.5 mmol / day (300 mg / day), it is necessary to reduce the dose or discontinue the drug.
Treatment: rehydration, use of loop diuretics (eg furosemide), glucocorticosteroids, calcitonin, bisphosphonates, in severe cases, hemodialysis.
If you accidentally overdose, you should induce vomiting and wash your stomach. Therapy is symptomatic.
It is therefore necessary to reduce the dose or discontinue the drug. In case of accidental overdose, it is necessary to induce vomiting, to wash the stomach. Therapy is symptomatic.
Storage conditions
At a temperature not exceeding 25 C.
Keep out of the reach of children.
Expiration
3 years. Do not use after the expiry date.
over-the-counter
pharmacies over-the-counter
tablet dosage form
Formulation
Bayer Pharma AG, Germany
