Description
Release form
Coated tablets.
Packing
10 pcs.
Pharmacological action
Blocker of histamine H1 receptors of the III generation.
Cetirizine affects the early stage of an allergic reaction and reduces the migration of eosinophils and limits the release of mediators in the late stage of an allergic reaction.
Cetirizine has virtually no anticholinergic and antiserotonin effects.
In therapeutic doses, does not cause a sedative effect.
Indications
Hay fever, allergic rhinitis, conjunctivitis, dermatitis, urticaria, Quincke edema.
Contraindications
Renal failure, pregnancy, lactation, hypersensitivity to the components of cetirizine.
Special instructions
If you exceed a dose of 10 mg / day, your ability to react quickly may worsen.
At recommended doses, it does not enhance the action of ethanol (at a concentration of not more than 0.8 g / l), however, it is recommended to refrain from using it during treatment.
During the treatment period, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require an increased concentration of attention and speed of psychomotor reactions.
Composition
1 tablet contains:
cetirizine dihydrochloride 10 mg.
Dosage and administration of
cetirizine is taken orally. Adults and children over 12 years of age – 10 mg / day. in 1-2 doses. Children aged 2-6 years – 5 mg / day. in 1-2 doses.
In patients with moderate or severe renal failure, the dose of cetirizine should be reduced by 2 times.
Side effects
Possible: dry mouth, drowsiness, headache, fatigue.
Rarely: skin manifestations of allergic reactions, angioedema.
In some cases: dyspepsia, agitation.
Drug interaction
Pharmacokinetic interaction with pseudoephedrine, cimetidine, ketoconazole, erythromycin, azithromycin, diazepam and glipizide.
Co-administration with theophylline (400 mg / day) leads to a decrease in the total clearance of cetirizine (the kinetics of theophylline does not change). Myelotoxic drugs increase the manifestation of hematotoxicity of the drug.
Overdose
Symptoms (occur when taking a single dose of 50 mg) – dry oral mucosa, drowsiness, urinary retention, constipation, anxiety, irritability.
Treatment: gastric lavage, the appointment of symptomatic drugs. There is no specific antidote. Hemodialysis is ineffective.
Storage Conditions
In a dark place at 2-25 ° C.
Deystvuyuschee substances
Cetirizine
Form of Treatment
tablets
Indications
pollen allergy, allergic rhinitis, urticaria, atopic dermatitis, Allergy, Dermatosis, Itching, Allergic conjunctivitis, Quincke’s edema
Possible product names
CETIRIZIN DS 0.01 N10 TABLE P / O
Cetirizine DS tab p / p / o 10m 10g unitary enterprise
TSETIRIZIN DS TAB.P / O Plen. 10 MG No. 10
Cetirizine DS tablets 10 mg 10 pcs.
Cetirizine DS tablets 10 mg, 10 pcs.
Danafa Pharmaceutical Joint Vietnam