Description
Latin name
Clindovit
Release form
Gel.
Packaging
In a tube of 30 g of gel. In a cardboard box 1 tube.
Pharmacological action
Gel Clindovit 1% is an antibiotic from the group of lincosamides.
– Active against all strains of Propionibacterium acnes.
MIC – 0.4 mcg / ml.
Inhibits protein synthesis in a microbial cell by interacting with 50S ribosome subunits.
Clindamycin phosphate is not active in vitro, but after application to the skin, it is rapidly hydrolyzed by phosphatases in the ducts of the sebaceous glands with the formation of clindamycin, which has antibacterial activity. After application to the skin, the amount of free fatty acids on the surface of the skin decreases from about 14% to 2%.
Indications
Treatment for acne (acne vulgaris).
Contraindications
– Crohn’s disease.
– ulcerative colitis (including a history of).
– Pseudomembranous colitis (including a history of).
– Hypersensitivity to clindamycin or lincomycin.
Caution:
– In patients under 12 years of age (safety and efficacy data not available).
– Betweenlactation (breastfeeding).
– In patients predisposed to the development of allergic reactions.
– While taking muscle relaxants.
Use during pregnancy and lactation
Clindovit can be used externally during pregnancy if the intended benefit of the therapy to the mother outweighs the potential risk to the fetus.
If necessary, use during lactation, breastfeeding is recommended to be discontinued.
Composition of
1 g of gel for external use contains:
Clindamycin (in the form of phosphate) 10 mg.
Excipients:
Methyl parahydroxybenzoate (nipagin),
allantoin,
tocopherol phosphate lauryliminodipropionate disodium,
propylene glycol,
macrogol 400 (sodium copolymer copolymer,
olymer copolymer, srdl copolymer, srdl copolymer, srd
purified water
Dosage and administration
The drug is used externally.
Gel is applied in a thin layer on the affected part of previously cleaned and dried skin 2-3 times / day. To obtain a therapeutic effect, treatment should be continued for 6-8 weeks, and if necessary, you can continue up to 6 months.
Side effects
The drug is usually well tolerated.
– Local reactions: Possible irritation (at the place of application), burning, itching, dry skin, erythema, peeling, increased secretion of sebum, contact dermatitis.
– Systemic reactions: Pseudomembranous enterocolitis (the likelihood of development is with systemic absorption of clindamycin).
Storage Conditions
Store at 15 ° C to 25 ° C.
Shelf life
2 years.
Deystvuyushtee substance
Clindamycin
Appointment Appointment
For adults, children over 12 years
Akrikhin CPC JSC, Russia
