clobetasol – Cloveit cream 0.05% 25 g

$19.00

Description

release form

Cream for external use.

Packaging

Tuba 25 g.

Pharmacological action

Cloveit is a synthetic corticosteroids for external use. It has a pronounced anti-inflammatory and anti-allergic effect. It is assumed that the drug reduces the inflammatory process by inhibiting the production of prostaglandins and leukotrienes, which leads to blocking the activity of phospholipase A2 and reducing the release of arachidonic acid from phospholipids of cell membranes. Antiallergic effect is due to the suppression of local allergic reactions. As a result of local vasoconstrictor action, exudative reactions are reduced, protein synthesis, and collagen deposition are reduced. It accelerates the breakdown of proteins in the skin and inhibits proliferative processes.

Indications

seborrheic dermatitis

contact eczema

atopic dermatitis

long-term psoriasis

erythematous lichen

erythema multiforme

discoid lupus erythematosus srdlk sharp red sard itching, or with excessive keratosis, when treatment with weaker corticosteroids is ineffective

Contraindications

Hypersensitivity to clobetasol propionate, to other corticosteroids, to other components of the drug bacterial, viral and fungal infections of the skin pink and ordinary acne, perioral dermatitis after vaccination, children under 12 years of age, pregnancy and lactation.

Special instructions

Avoid prolonged use. With prolonged use on large areas of the skin, the incidence of side effects and the risk of edema, hypertension, hyperglycemia, and a decrease in the body’s resistance increase.

With external use of clobetasol propionate, inhibition of the pituitary-adrenal system is possible. This is expressed in a decrease in pituitary gland production of ACTH, a decrease in the level of cortisol in the blood, and the development of iatrogenic Cushing’s syndrome. The listed changes pass after the termination of treatment. The function of the adrenal cortex should be regularly monitored by determining the levels of cortisol in the blood and urine after stimulation of the adrenal glands through ACTH.

In case of infection in the area of application of the drug, appropriate antibacterial or antifungal treatment should be prescribed. If the symptoms of the infection do not go away, you must stop using Cloveit until the infection is completely cured.

Avoid applying the drug to the skin in the eyelids in patients with closed or open-angle glaucoma, with cataracts due to the risk of exacerbation of the disease. On the skin of the face, in the axillary and inguinal areas, the drug should be used only in cases of special need, given the increased absorption and increased risk of side effects (telangiectasia, perioral dermatitis).

Use with caution in atrophic conditions of subcutaneous fat, especially in the elderly.

Cloveit may enhance the effects of immunosuppressants and weaken the effects of immunostimulating drugs.

Composition of

1 g of cream contains:

Active substances: clobetasol propionate 500 mcg.

Auxiliary ingredients: white petrolatum – 252 mg propylene glycol – 100 mg polysorbate 40 – 53 mg disodium edetate – 0.2 mg chlorocresol – 1 mg glyceryl monostearate – 31 mg liquid paraffin – 23 mg cetostearyl alcohol (cetyl alcohol and stearyl alcohol 6 : 4) – 69 mg of triglycerides of octanoic and decanoic acids – 15 mg of sodium citrate – 0.5 mg of silicon colloidal dioxide – 1 mg of citric acid – 0.5 mg of hemoderm flavor 841 – 0.3 mg of purified water – up to 1000 mg.

Dosage and administration

A small amount of cream is applied to the affected surface of the skin 1-2 times a day, rubbing easily.

Do not use the drug under an occlusive dressing and treat without interruption for more than 2 weeks.

Side effects of

Local reactions: acne, steroid purpura, inhibition of epidermal growth, atrophy of the subcutaneous tissue, dry skin, hypertrichosis or alopecia, hypo- or hyperpigmentation of the skin, atrophy of the skin and striae, telangiectasia, perioral infection, hairline dermatitis .

Systemic effect: edema, arterial hypertension, decreased resistance (resorptive effect when used under an occlusive dressing).

Allergic reactions: rarely – urticaria or maculopapular rash.

From the sensory organs: glaucoma, cataract (when applied to the skin of the eyelids).

Storage conditions

Keep out of the reach of children at a temperature not exceeding 25 ° C. Do not freeze.

active substance

Clobetasol

drugstore conditions

drugstore

lekarstvennaja form

cream

Elf Farmzavod, Poland