Description
Release form
Topical cream
Pharmacological action
Candide is a broad-spectrum antifungal.
The antimycotic effect of the active substance, clotrimazole (an imidazole derivative), is associated with impaired synthesis of ergosterol, which is part of the cell membrane of fungi, which changes the membrane permeability and causes subsequent cell lysis.
It acts fungistatically in small concentrations, fungicidal in large concentrations, and not only on proliferating cells.
In fungicidal concentrations, it interacts with mitochondrial and peroxidase enzymes, resulting in an increase in the concentration of hydrogen peroxide to a toxic level, which also contributes to the destruction of fungal cells.
Effective against dermatophytes, yeast-like and mold fungi, as well as the causative agent of colorful lichen (Pityriasis versicolor) and the pathogen of erythrasma. It has an antimicrobial effect against gram-positive (staphylococci, streptococci) and gram-negative bacteria (Bacteroides, Gardnerella vaginalis), as well as against Trichomonas vaginalis.
Indications
dermatophytosis of the head (including the face), body, foot
mycosis of nails
multicolored lichen
candidiasis of the skin
candida paronychia
candida vulvitis
candida balanitis
candidiasis of the external genitalia and anus
fungal diaper dermatitis
.
Contraindications
specific skin lesions (including tuberculosis, chickenpox, herpes simplex, measles, syphilis)
skin reactions at the site of vaccination
hypersensitivity to the components of the drug.
Use during pregnancy and lactation
Safety of the use of the drug Candide during pregnancy and lactation has not been established.
Therefore, the administration of the drug in large quantities or for a long time during these periods should be avoided.
Ingredients
1 g cream contains:
Active ingredient:
Clotrimazole 10 mg
Excipients:
Propylene
Liquid paraffin
cetomacrogol emulsifying wax
White petrolatum
benzyl alcohol
Methylparaben
Propylparaben
Anhydrous sodium phosphate
Sodium phosphate monobasic
butylhydroxytoluene
Purified Water
Dosage and administration
The required amount of cream is rubbed onto previously washed and dry affected skin 2-3 times a day.
Treatment should be continued for another 2-4 weeks after the disappearance of clinical symptoms in order to ensure mycological cure and prevent relapse.
Side effects
Itching, burning and swelling of the vaginal mucosa, vaginal discharge, headache, gastralgia, frequent urination, intercurrent cystitis, burning sensation in the penis of the sexual partner, pain during intercourse.
Overdose
Using the drug at high doses does not cause any life-threatening reactions and conditions.
Symptoms (in case of unintended use of the drug inside):
anorexia, nausea, vomiting, gastralgia, liver dysfunction rarely – drowsiness, hallucinations, pollakuria, skin allergic reactions.
Treatment:
purpose of activated charcoal, if necessary – no symptomatic therapy for a specific antidote.
Storage conditions
The product should be stored in a dry,
, protected from light at a temperature not exceeding 25 ° C.
shelf life
3 years
Deystvuyushtee substance
Clotrimazole
Conditions for dispensing from pharmacies
Without a prescription
dosage form
cream
Possible product names
CANDID 1% 20G. CREAM
Candide 1% Cream 20g
Candide 1% cream d / outdoor approx. 20g Tuba
CANDID 20,0 CREAM
Candide cream 1%, 20 g
Glenmark Pharmaceuticals Ltd., India
