Description
Description
Aerius No. 10 – Allergy pills, active ingredient desloratadine.
Looking for an allergy remedy
Erius tablets is the latest generation of the drug, with triple activity against allergies: anti-inflammatory, antihistamine and anti-allergic (1).
Erius eliminates 10 allergy symptoms: – Itching, redness and lacrimation of the eyes.
– Congestion, sneezing, itching, and nasal discharge.
– Itching of the sky.
– Itchy skin, rash.
The drug is indicated: – for seasonal and perennial allergic rhinitis,
– for hives.
Unlike some other generation II antihistamines (2), Erius does not interact with drugs and alcohol (3), does not cause drowsiness (possible frequency is less than 1 in 10,000 patients).
The drug is taken 1 time per day, is able to start acting within 30 minutes after administration and have an effect within 24 hours. Adults and adolescents from 12 years old: 1 tablet (5 mg) once a day.
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1. Canonica GW., Blaiss M. Antihistaminic, anti-inflammatory, and antiallergic properties of the nonsedating second-generation antihistamine desloratadine: a review of the evidence. World Allergy Organ J. 2011 Feb 4 (2): 47-53.
2. For example, with the combined use of fexofenadine with erythromycin or ketoconazole, the concentration of fexofenadine in the plasma increases, aluminum- or magnesium-containing antacids reduce the bioavailability of fexofenadine (Allegra instructions for use) the simultaneous use of cetirizine with alcohol or drugs that depress the central nervous system can further reduce the concentration of attention and speed of reactions (Zirtek instructions for use).
3. Alcohol should be used with caution.
Release form
Coated tablets.
packaging 10 pcs
Pharmacological action
Erius is a long-acting antihistamine, a blocker of peripheral histamine H1 receptors.
Desloratadine is the primary active metabolite of loratadine. Inhibits a cascade of allergic inflammation reactions, incl. the release of pro-inflammatory cytokines, including interleukins IL-4, IL-6, IL-8, IL-13, the release of pro-inflammatory chemokines, production of superoxide anions activated by polymorphonuclear neutrophils, adhesion and chemotaxis of eosinophils, isolation of adhesion molecules such as P-selectin, IgE – mediated release of histamine, prostaglandin D 2 and leukotriene C4.
Thus, it prevents the development and facilitates the course of allergic restocks, has antipruritic and antiexudative action, reduces capillary permeability, prevents the development of tissue edema, smooth muscle spasm.
The drug has no effect on the central nervous system, practically does not have a sedative effect (does not cause drowsiness) and does not affect the speed of psychomotor reactions.
Does not cause prolongation of the QT interval on the ECG.
The action of Erius syrup begins within 30 minutes after ingestion and lasts for 24 hours.
Indications
– Seasonal (hay fever) and perennial allergic rhinitis (elimination or relief of sneezing, nasal congestion, mucus discharge from the nose, itchy nose, itchy palate, itching and redness of the eyes, lacrimation).
– Chronic idiopathic urticaria (reduction or elimination of skin itching, rash).
Contraindications
– hypersensitivity to the components of the drug
– pregnancy
– lactation (breastfeeding)
– under 12 years old
– hereditary diseases (intolerance to fructose, impaired glucose / galactose intolerance or deficiency) with the presence of sucrose and sorbitol in the syrup.
Caution: the drug should be used in cases of severe renal failure.
Use during pregnancy and lactation
Use of the drug during pregnancy is not recommended due to the lack of clinical data on the safety of its use in this period.
Desloratadine is excreted in breast milk, so the use of Erius during breastfeeding is not recommended.
Composition
1 tab. contains:
Active ingredient:
– desloratadine 5 mg.
Excipients:
calcium hydrogen phosphate dihydrate,
microcrystalline cellulose,
corn starch,
talc.
Shell composition:
carnauba wax,
white wax,
film coating blue and transparent (lactose monohydrate, hypromellose, titanium dioxide, macrogol, aluminum blue varnish FD&C No. 2 (indigo carmine, E132).
Dosing and Administration
Adults and adolescents 12 years of age and older are prescribed 5 mg once a day, regardless of food intake, preferably at the same time of day.
The tablet should be swallowed whole without chewing, washed down with a small amount of water.
Side effects of
When using the drug, increased fatigue (1.2%), dry mouth (0.8%), headache (0.6%) were noted.
From the cardiovascular system: very rarely – tachycardia, palpitations.
From the digestive system: very rarely – increased activity of liver enzymes, increased bilirubin concentration.
Allergic reactions: very rarely – anaphylaxis, rash.
Drug Interaction
Erius does not enhance the effects of ethanol on the CNS.
Eating does not affect the effectiveness of the drug.
Storage conditions
Keep out of the reach of children at a temperature not exceeding 30 ° C
Expiration
2 years.
Active substance
desloratadine
Sardlkp pharmacy terms and conditions Over-the-counter
Dosage form
Dosage form
tablets
Bayer Pharma AG, Germany
