Dexamethasone neomycin polymyxin B – Maxitrol Eye Drops 5 ml

$23.00

Description

Latin name

Maxitrol

Packaging

In a dropper bottle 5 ml of solution. In packing 1 bottle dropper.

Pharmacological action

Maxitrol is a combined preparation for topical use in ophthalmology. Glucocorticosteroid + antibiotics (aminoglycoside and cyclic polypeptide).

Neomycin

It has a bactericidal effect, disrupting the synthesis of bacterial cell protein. Active against: Staphylococcus aureus, Corynebacterium diphteriae, Streptococcus viridans, Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris, Aerobacter aerogenes, Haemophilus influenzae.

Polymyxin

B The mechanism of action of polymyxin B is mainly due to the blockade of the permeability of the cytoplasmic membrane of bacterial cells. Active against: Pseudomonas Aeruginosa, Aerobacter aerogenes, Escherichia coli, Klebsiella pneumoniae, Koch-Weeks bacillus.

Dexamethasone

Glucocorticosteroid. It has anti-inflammatory, anti-allergic and desensitizing effects. It has an antiexudative effect. Dexamethasone effectively inhibits inflammatory processes.

The combination of glucocorticosteroid with antibiotics can reduce the risk of infection.

Indications

Infections of the eye and its appendages: Blepharitis.

Conjunctivitis.

Keratoconjunctivitis.

Blepharoconjunctivitis.

Keratitis.

Iridocyclitis.

Prevention of postoperative infectious complications.

Contraindications

Individual hypersensitivity to the components of the drug.

Viral eye diseases (including keratitis caused by Herpes simplex, chicken pox).

Mycobacterial infection of the eyes.

Tuberculosis eye disease.

Shingles.

Fungal eye disease.

Condition after removal of a foreign body of the cornea.

Purulent infection of the mucous membrane of the eye and eyelids caused by microorganisms resistant to neomycin.

Purulent corneal ulcer.

Use with caution in: Glaucoma.

Cataract.

Use during pregnancy and lactation

There is no sufficient experience with the use of the drug during pregnancy and lactation.

It is possible to use it to treat pregnant women as prescribed by the attending physician if the expected therapeutic effect exceeds the risk of developing possible side effects.

Discontinue use of the drug during lactation.

Composition of

1 ml of solution contains:

Active ingredients

Dexamethasone 1.0 mg.

Neomycin sulfate 3500 IU.

Polymyxin B Sulfate 6000 IU.

Excipients

Benzalkonium chloride solution, equivalent to benzalkonium sodium chloride, polysorbate 20, hypromellose * (4000 mPa.s), concentrated hydrochloric acid and / or sodium hydroxide to adjust pH, purified water.

Dosage and Administration

Topically.

With a mild infection

1-2 drops in the conjunctival sac 4-6 times a day.

In an acute severe infectious process

1-2 drops in the conjunctival sac every 60 minutes, with a decrease in the frequency of drug installations as inflammation decreases.

Side effects

Local. An allergic reaction, accompanied by itching and swelling of the eyelids, conjunctival hyperemia. Side effects due to the steroid component: increased intraocular pressure with possible subsequent development of glaucoma, damage to the optic nerve and visual fields (when using the drug for more than 10 days, monitoring of intraocular pressure is necessary), posterior subcapsular cataract, slowing the healing process. Topical use of steroids in diseases that cause thinning of the cornea or sclera can lead to their perforation.

Secondary infection. The development of a secondary infection is observed after the use of combined preparations containing GCS in combination with antibiotics. With prolonged use of steroids, the development of fungal infections of the cornea is possible. The appearance on the cornea of non-healing ulcers after prolonged treatment with steroid drugs may indicate the development of fungal invasion. Secondary bacterial infection can occur as a result of suppression of the protective reaction of the patient’s body.

Drug Interaction

Interaction with other medicines is currently unknown.

When used with other topical ophthalmic drugs, the interval between use should be at least 10 minutes.

Storage Conditions

Store at 8-30 ° C.

Shelf life

2 years.

Deystvuyushtee substance

Dexamethasone, Neomycin, Polymyxin B

Terms and conditions

prescription

Dosage form

eye drops

Possible product names

Maxitrol 0.1% Ch. Drops 5ml.Fl.-dropper.plastic. M

Maxitrol 0.1% Ch. Drops 5ml.Fl.-dropper.plastic. M /! Till 11.14g /

MAXITROL 5ML GL DROPS FLAK / KAP

MAXITROL 5ML. GL. DROPS

MAXITROL GL. DROPS 5ML

Alkon, USA