Description
Pharmacological action
Glucose is one of the most easily assimilated sugars. It is well absorbed into the blood, and its excess enters the liver and muscles, where it turns into glycogen. In the body, it breaks down with the formation of energy, which provides heat, the work of muscles and other tissues. Glucose also stimulates the synthesis of hormones and enzymes in animals, increases the body’s defenses. With the intravenous administration of a hypertonic glucose solution, the osmotic pressure of the blood rises, the flow of fluid from the tissues to the blood increases, metabolic processes increase, the detoxification function of the liver improves, the contractile activity of the heart muscle increases, the vessels expand, diuresis increases.
Indications
Toxic infections, infectious diseases, various intoxications (poisoning with drugs, hydrocyanic acid and its salts, carbon monoxide, aniline, arsenous hydrogen and other substances), liver diseases (hepatitis, cirrhosis, dystrophy and liver atrophy), decompensation pulmonary edema, hemorrhagic diathesis and many other pathological conditions. In ruminants, it is prescribed for gastrointestinal diseases with the effects of intoxication, hypotension, atony of the stomach, as well as for acetonemia, postpartum hemoglobinuria, ketonuria and toxemia. Glucose solutions are prescribed to weak and depleted animals as an energy and dietary remedy.
Contraindications
Hyperglycemia.
Special instructions
Livestock products after glucose solution can be used without any restrictions.
Composition
5% glucose solution – isotonic. Solutions of 10%, 25% and 40% are hypertonic. They are a clear, colorless or slightly yellowish liquid sweet in taste, pH 3.0-4.0.
Dosage and administration of
Depending on the severity of the disease, the drug is administered to animals orally or intravenously 1 to 2 times a day in the following doses (in ml per animal):
Animal species
5% glucose solution
10% glucose solution
25% glucose solution
40% glucose solution
Cattle
600 – 3000
300 – 1500
100 – 600
75 – 370
Horses
600 – 2400
300 – 1200
100 – 500
75 – 300
Sheep, goats
100 – 600
60 – 300
25 – 120
10 – 75
Pigs
200 – srdlp 100 – srdlp 50 – 120
20 – 75
Dogs
50 – 500
20 – 250
10 – 100
5 – 50
An isotonic (5%) glucose solution is administered subcutaneously and intravenously. The dose volume and timing of use depend on the weight of the animal and the course of the disease.
Side effects
With proper use and dosage, side effects are usually not observed.
Storage conditions
In a dry, dark place at a temperature of 0 to 25 ° C.
Shelf life
2 years.
Active ingredient
Dextrose
Dosage form
injection
