Description
Release form
Gel for external use.
Pharmacological action
Dicloran Plus – local anti-inflammatory, analgesic.
Pharmacodynamics
NSAIDs for external use. It has a local analgesic, anti-inflammatory and antiexudative effect. Diclofenac sodium and methyl salicylate are NSAIDs, the mechanism of action of which is due to the suppression of GHG synthesis. When applied topically, they reduce pain and inflammation in the joints, morning stiffness and swelling of the joints, contribute to an increase in range of motion.
The main component of flaxseed oil is -linolenic acid, which also has anti-inflammatory effects.
Levomenthol causes irritation of nerve endings, has a local distracting and mild analgesic effect, causes a feeling of coolness at the site of application of the drug.
Pharmacokinetics
When applied topically, diclofenac sodium, methyl salicylate, and linseed oil are absorbed and penetrate the subcutaneous tissue, muscle tissue, and joint capsule.
Indications of
diseases of the musculoskeletal system: rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, osteoarthritis of the peripheral joints and spine, rheumatic soft tissue lesions
myalgia of rheumatic and non-rheumatic origin soft tissue injury
.
Contraindications
violation of the integrity of the skin
aspirin triad
III trimester of pregnancy
lactation (breastfeeding)
children under 6 years old
increased sensitivity to diclofenac, amethyl or other, methylated
Special instructions
The drug should be applied only to intact skin, avoiding contact with open wounds.
Dicloran Plus should not be used under an occlusive dressing.
Avoid contact with eyes and mucous membranes.
Composition
2 mg
butylhydroxytoluene – 2 mg
benzyl alcohol – 10 Ñl
disodium edetate – 1 mg
diethylamine – 7.1 Ñl
carbomer 980 – 10.8 mg
citric acid monohydrate – 1 mg hydrochloride hydrochloride – 35 mg
propylene glycol – 100 mg
water – sc. required up to 1 g
Dosage and administration
Locally, apply a strip of Dikloran gel plus 4-8 cm on a painful area of ??the skin and rub it lightly, 2-3 times a day.
Duration of treatment without medical advice is no more than 10 days.
Side effects
Dermatological reactions: eczema, photosensitivity, contact dermatitis (including itching, hyperemia, swelling of the treated skin area, papules, vesicles, peeling).
Allergic reactions: generalized skin rash, urticaria, angioedema, bronchospastic reactions.
Drug Interactions
Diclofenac may enhance the effects of photosensitizing medications.
No clinically relevant interactions with other drugs have been described.
Overdose of
When used topically in recommended doses, the extremely low systemic absorption of the active components of the drug makes overdosing almost impossible.
In case of accidental ingestion, systemic side effects may develop.
Ingestion: gastric lavage, induction of vomiting, intake of activated charcoal, forced diuresis, symptomatic therapy.
Dialysis is ineffective due to the high degree of binding of diclofenac to plasma proteins (about 99%).
Storage conditions
The product should be stored out of the reach of children at a temperature not exceeding 25 ° C.
The Expiration of
is 3 years.
active substance
Diclofenac
Terms leave through pharmacies
without prescription
lekarstvennaja form
gel naruzhnej Application
